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PLP1 wt Allele

Known as: PMD, PLP/DM20, Proteolipid Protein 1 (Pelizaeus-Merzbacher Disease, Spastic Paraplegia 2, Uncomplicated) wt Allele 
Human PLP1 wild-type allele is located in the vicinity of Xq22 and is approximately 16 kb in length. This allele, which encodes myelin proteolipid… 
National Institutes of Health

Related topics

Related topics

5 relations
Homo sapiensNeurogenesisPelizaeus-Merzbacher DiseaseSPASTIC PARAPLEGIA 2, X-LINKED (disorder)

Papers overview

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2002
2002
iWalk: Interactive Out-Of-Core Rendering of Large Models
We present iWalk, a system for interactive out-of-core rendering of large models on an inexpensive PC. The system uses a new… 
Highly Cited
2001
Highly Cited
2001
Oral administration of insulin to neonates suppresses spontaneous and cyclophosphamide induced diabetes in the NOD mouse.
Oral administration of autoantigens to adult mice is an effective means of suppressing experimental autoimmune diseases including… 
Highly Cited
2001
Highly Cited
2001
Myelin proteolipid proteins promote the interaction of oligodendrocytes and axons
Although proteolipid protein (PLP) and its DM20 isoform are the major membrane proteins of CNS myelin, their absence causes… 
Highly Cited
2000
Highly Cited
2000
Homocysteine, folate, vitamin B-12 and vitamin B-6 in patients receiving antiepileptic drug monotherapy
Highly Cited
1999
Highly Cited
1999
Identification of a New Exon in the Myelin Proteolipid Protein Gene Encoding Novel Protein Isoforms That Are Restricted to the Somata of Oligodendrocytes and Neurons
The myelin proteolipid protein (PLP) gene (i.e., the PLP/DM20 gene) has been of some interest because of its role in certain… 
Highly Cited
1994
Highly Cited
1994
Intracellular transport and sorting of the oligodendrocyte transmembrane proteolipid protein
Delineating the properties and functions of the major central nervous system myelin proteins has been the focus of intensive… 
Highly Cited
1991
Highly Cited
1991
Pelizaeus-Merzbacher disease: a valine to phenylalanine point mutation in a putative extracellular loop of myelin proteolipid.
In the central nervous system, myelin proteolipid protein isoforms (PLP and DM20) play an essential structural role in… 
Highly Cited
1987
Highly Cited
1987
Arrest of proteolipid transport through the Golgi apparatus in Jimpy brain
SummaryImmunocytochemical investigations were performed on Jimpy and control mouse brains using three specific anti-myelin… 
Highly Cited
1981
Highly Cited
1981
Central nervous system myelin proteins and glycoproteins in vertebrates: A phylogenetic study
Highly Cited
1980
Highly Cited
1980
MMPL profiles of men referred for a pretrial psychiatric assessment as a function of offense type.
Gathered MMPI and demographic data on six groups of 25 men each who had been remanded by the courts to a maximum security… 
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