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PLCG2 protein, human

Known as: 1-Phosphatidylinositol Phosphodiesterase, 1-Phosphatidylinositol-4,5-Bisphosphate Phosphodiesterase Gamma 2, PLC-Gamma-2 
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (1265 aa, ~148 kDa) is encoded by the human PLCG2 gene. This protein plays a role… 
National Institutes of Health

Related topics

Related topics

19 relations
1-Phosphatidylinositol phosphodiesterase1-Phosphatidylinositol-4,5-bisphosphate phosphodiesteraseB Cell Receptor Signaling PathwayERBB Family Signaling Pathway

Broader (1)

Phospholipase C gamma 2

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Silencing of phosphoinositide-specific phospholipase C ε remodulates the expression of the phosphoinositide signal transduction pathway in human osteosarcoma cell lines.
BACKGROUND Ezrin, a member of the ezrin-radixin-moesin family, is involved in the metastatic spread of osteosarcoma. Ezrin binds… 
2008
2008
SFC로 설계된 PLC 제어에서 효율적인 자기진단 기능
PLC를 사용한 제어 시스템을 설계할 때 여러 종류의 표준언어 중 LD언어가 가장 많이 사용되지만, SFC를 사용하면 제어의 흐름을 알기 쉽고 유지보수가 용이하며, 프로그램의 기술성이 뛰어나다. 그러나 SFC… 
2002
2002
Alboluxin, a Snake C-type Lectin from Trimeresurus albolabris Venom is a Potent Platelet Agonist acting via GPIb and GPVI
Summary Alboluxin, a potent platelet activator, was purified from Trimeresurus albolabris venom with a mass of 120 kDa non… 
2001
2001
Phosphatidylinositol 3-kinase-dependent translocation of phospholipase Cgamma2 in mouse megakaryocytes is independent of Bruton tyrosine kinase translocation.
Activation of the collagen receptor glycoprotein VI (GPVI) by a collagen-related peptide (CRP) induces stimulation of platelets… 
1999
1999
Binding of phosphatidylinositol-specific phospholipase C to phospholipid interfaces, determined by fluorescence resonance energy transfer.
1996
1996
Cloning and functional analysis of the hematopoietic cell-specific phospholipase C(gamma)2 promoter.
Phospholipase C(gamma)2 (PLCgamma2) is a phospholipid-converting enzyme which, upon receptor stimulation, is activated within… 
1996
1996
Negative signaling via FcgammaRIIB1 in B cells blocks phospholipase Cgamma2 tyrosine phosphorylation but not Syk or Lyn activation.
Crosslinking of the B cell antigen receptor surface immunoglobulin induces tyrosine phosphorylation and activation of the Src… 
1994
1994
Ethanol-induced alteration in activities of cerebral phosphatidylinositol 4,5-biphosphate-specific and cytosolic phospholipase C in the brain: analysis using NG 108-15 cells and brains from ethanol…
1992
1992
Isolation of a Polyphosphoinositide-phospholipase C (Type β) from Cytosolic and Membrane Fractions of Human Platelets.
Human platelet cytosol contains several phosphoinositide-specific phospholipases C (PLCs) separable by stepwize ion-exchange… 
1988
1988
Does phospholipase C inhibit fusion between hamster sperm and zona-free eggs?
Previous studies (Hirao and Yanagimachi: Gamete Res. 1:3-12, 1978) have found that phospholipase C (PLC) preparations inhibit… 
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