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PLAU gene

Known as: UROKINASE, PLASMINOGEN ACTIVATOR, URINARY, Plasminogen Activator, Urokinase Gene 
This gene plays a role in blood coagulation and the regulation of monocyte/macrophage functions.
National Institutes of Health

Related topics

Related topics

6 relations
Alzheimer's DiseaseHydrolysisProteolysisRecombinant Urokinase

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PLAU wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1993
1993
Inhibition of urokinase synthesis and cell surface binding alters the motile behavior of embryonic endocardial-derived mesenchymal cells in vitro.
The expression of the serine protease urokinase is elevated during the epithelial-mesenchymal transformation of the endocardium… 
Review
1992
Review
1992
Urokinase-catalyzed plasminogen activation at the monocyte/macrophage cell surface: a localized and regulated proteolytic system.
In the adult organism, monocytes and macrophages are among the few cell types that can migrate within and between body… 
1992
1992
Identification and characterization of urokinase receptors in natural killer cells and T‐cell‐derived lymphokine activated killer cells
Highly Cited
1991
Highly Cited
1991
Complementation between urokinase-producing and receptor-producing cells in extracellular matrix degradation.
The respective roles of urokinase plasminogen activator (u-PA) and the u-PA receptor in extracellular matrix degradation was… 
Highly Cited
1990
Highly Cited
1990
Bovine AlphaS1-Casein Gene Sequences Direct High Level Expression of Active Human Urokinase in Mouse Milk
We have produced a line of transgenic mice carrying a hybrid bovine αs1 casein/human urokinase gene. Bovine αs1-casein gene… 
1990
1990
Isolation of urokinase by affinity ultrafiltration
A water‐soluble, ligand‐bound polymer has been synthesized for the purpose of isolation of urokinase, an important plasminogen… 
1989
1989
Lysis of Intraventricular Blood Clot with Urokinase in a Canine Model: Part 2
It was determined from in vitro experiments that the minimal dose of urokinase required to lyse 10 ml of clotted canine blood… 
1987
1987
Thrombolysis by a fibrin-specific antibody Fab'-urokinase conjugate.
Highly Cited
1984
Highly Cited
1984
Isolation and characterization of a urokinase-type plasminogen activator (Mr = 54,000) from cultured human endothelial cells indistinguishable from urinary urokinase.
1975
1975
The importance of the preactivation peptide in the two-stage mechanism of human plasminogen activation.
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