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PKN2 gene
Known as:
PRKCL2
, PROTEIN KINASE N2
, PROTEIN-KINASE C-RELATED KINASE 2
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National Institutes of Health
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Related topics
Related topics
3 relations
PKN1 gene
low-density-lipoprotein-receptor kinase activity
protein kinase N2
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
The Yersinia Virulence Factor YopM Hijacks Host Kinases to Inhibit Type III Effector-Triggered Activation of the Pyrin Inflammasome.
Lawton K. Chung
,
Y. Park
,
+5 authors
J. Bliska
Cell Host and Microbe
2016
Corpus ID: 18962957
Highly Cited
2010
Highly Cited
2010
Delineation of Regions of the Yersinia YopM Protein Required for Interaction with the RSK1 and PRK2 Host Kinases and Their Requirement for Interleukin-10 Production and Virulence
Joseph B. McPhee
,
P. Mena
,
J. Bliska
Infection and Immunity
2010
Corpus ID: 8923701
ABSTRACT The YopM protein of Yersinia sp. is a type III secreted effector that is required for virulence in murine models of…
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Review
2008
Review
2008
Genetic analysis of recently identified type 2 diabetes loci in 1,638 unselected patients with type 2 diabetes and 1,858 control participants from a Norwegian population-based cohort (the HUNT study)
J. Hertel
,
S. Johansson
,
+10 authors
P. Njølstad
Diabetologia
2008
Corpus ID: 13165951
Aims/hypothesisRecent genome-wide association studies performed in selected patients and control participants have provided…
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Highly Cited
2006
Highly Cited
2006
Phosphorylation of Tyr1214 within VEGFR-2 Triggers the Recruitment of Nck and Activation of Fyn Leading to SAPK2/p38 Activation and Endothelial Cell Migration in Response to VEGF*
Laurent Lamalice
,
François Houle
,
J. Huot
Journal of Biological Chemistry
2006
Corpus ID: 30087862
VEGFR-2 is the major receptor that regulates the different functions of VEGF in adults. We have previously reported that…
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Highly Cited
2005
Highly Cited
2005
Binding of Activated α2-Macroglobulin to Its Cell Surface Receptor GRP78 in 1-LN Prostate Cancer Cells Regulates PAK-2-dependent Activation of LIMK*
U. K. Misra
,
Rohit Deedwania
,
S. Pizzo
Journal of Biological Chemistry
2005
Corpus ID: 25784397
Two characteristics of highly malignant cells are their increased motility and secretion of proteinases allowing these cells to…
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Highly Cited
2003
Highly Cited
2003
Caspase-activated PAK-2 Is Regulated by Subcellular Targeting and Proteasomal Degradation*
R. Jakobi
,
C. C. McCarthy
,
M. A. Koeppel
,
D. Stringer
Journal of Biological Chemistry
2003
Corpus ID: 37417702
p21-activated protein kinases (PAKs) are a family of serine/threonine protein kinases that are activated by binding of the p21 G…
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Highly Cited
2000
Highly Cited
2000
Further evidence that 3‐phosphoinositide‐dependent protein kinase‐1 (PDK1) is required for the stability and phosphorylation of protein kinase C (PKC) isoforms
A. Balendran
,
Gregor Hare
,
A. Kieloch
,
Michayla R. Williams
,
D. Alessi
FEBS Letters
2000
Corpus ID: 19232077
Highly Cited
1996
Highly Cited
1996
Isolation of a NCK-associated Kinase, PRK2, an SH3-binding Protein and Potential Effector of Rho Protein Signaling*
L. Quilliam
,
Q. Lambert
,
+7 authors
C. Der
Journal of Biological Chemistry
1996
Corpus ID: 29440754
The NCK adapter protein is comprised of three consecutive Src homology 3 (SH3) protein-protein interaction domains and a C…
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Highly Cited
1995
Highly Cited
1995
Cloning and expression patterns of two members of a novel protein-kinase-C-related kinase family.
R. Palmer
,
J. Ridden
,
P. Parker
European Journal of Biochemistry
1995
Corpus ID: 40766420
The cDNA clones for two members of a novel protein kinase family were isolated and sequenced. These protein-kinase-C-related…
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Highly Cited
1979
Highly Cited
1979
Host range conferred by the virulence-specifying plasmid of Agrobacterium tumefaciens
Joyce E. LOPERt
,
Clarence
,
I.
,
Kado
Journal of Bacteriology
1979
Corpus ID: 21054828
The host range of Agrobacterium tumefaciens 1D1109, known to induce crown gall only on grapevine (Vitis spp.), was extended to…
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