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PKN1 gene

Known as: PROTEIN KINASE N1, SERINE/THREONINE PROTEIN KINASE N, PKN-ALPHA 
This gene is involved in the phosphorylation of cytoskeletal intermediate filaments, cell migration and histone modification.
National Institutes of Health

Related topics

Related topics

10 relations
Cytoskeletal ModelingMigration, CellPKN1 protein, humanPKN2 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Dissecting Activation of the PAK1 Kinase at Protrusions in Living Cells*
The p21-activated kinase (PAK) 1 kinase, an effector of the Cdc42 and Rac1 GTPases, regulates cell protrusions and motility by… 
Highly Cited
2008
Highly Cited
2008
Pak1 and Pak2 Mediate Tumor Cell Invasion through Distinct Signaling Mechanisms
ABSTRACT Pak kinases are thought to play critical roles in cell migration and invasion. Here, we analyze the roles of Pak1 and… 
Highly Cited
2003
Highly Cited
2003
Vascular Endothelial Growth Factor Causes Translocation of p47phox to Membrane Ruffles through WAVE1*
Growth factors initiate cytoskeletal rearrangements tightly coordinated with nuclear signaling events. We hypothesized that the… 
2003
2003
Hyperosmotic-induced Protein Kinase N 1 Activation in a Vesicular Compartment Is Dependent upon Rac1 and 3-Phosphoinositide-dependent Kinase 1*
Protein kinase N 1 (PKN1), which in part resembles yeast protein kinase C, has been shown to be under the control of Rho GTPases… 
2001
2001
PKN delays mitotic timing by inhibition of Cdc25C: possible involvement of PKN in the regulation of cell division.
The role of PKN, a fatty acid- and Rho small GTPase-activated protein kinase, in cell-cycle regulation was analyzed… 
2001
2001
Endothelial kinin B1‐receptors are induced by myocardial ischaemia‐reperfusion in the rabbit
1 Kinin B1‐receptors are induced by various inflammatory stimuli. Since myocardial ischaemia‐reperfusion results in inflammation… 
Highly Cited
2000
Highly Cited
2000
Phosphorylation of protein kinase N by phosphoinositide-dependent protein kinase-1 mediates insulin signals to the actin cytoskeleton.
Growth factors such as insulin regulate phosphatidylinositol 3-kinase-dependent actin cytoskeleton rearrangement in many types of… 
Highly Cited
1999
Highly Cited
1999
Localization of the PAK1-, WASP-, and IQGAP1-specifying Regions of Cdc42*
The Rho family small GTPase Cdc42 transmits divergent intracellular signals through multiple effector proteins to elicit cellular… 
Highly Cited
1999
Highly Cited
1999
Reciprocal Signaling between Heterotrimeric G Proteins and the p21-stimulated Protein Kinase*
p21-activated protein kinase (PAK)-1 phosphorylated Gαz, a member of the Gαi family that is found in the brain, platelets, and… 
Highly Cited
1983
Highly Cited
1983
Magnetic field and magnetic isotope effects on photoinduced emulsion polymerization
The photochemically induced emulsion polymerization of styrene, methyl methacrylate, or acrylic acid is photosensitized by oil… 
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