PKCdelta
National Institutes of Health
Papers overview
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Nucleotides, released in response to mechanical or inflammatory stimuli, signal through P2 nucleotide receptors in many cell…
Our study identifies tyrosine phosphorylation as a novel protein kinase Cδ (PKCδ) activation mechanism that modifies PKC…
ADP is a critical regulator of platelet activation, mediating its actions through two G protein-coupled receptors (GPCRs), P2Y1…
Our laboratory is interested in understanding the regulation of NADPH oxidase activity in human monocyte/macrophages. Protein…
Activation of the inducible transcription factor nuclear factor κB (NF-κB) occurs in cells exposed to oxidative stress, and the…
The effects of OSM on proliferation and differentiation of osteosarcoma and nontransformed osteoblasts were analyzed. OSM…
Objective—We have recently demonstrated that protein kinase C (PKC) and Rho-kinase play important roles in coronary vasospasm in…
Sodium-dependent transporters clear extracellular glutamate in the mammalian CNS. Activation of protein kinase C (PKC) rapidly…
Protein kinase C (PKC) isoforms are phosphorylated on tyrosine in the response of cells to oxidative stress. The present studies…
Human involucrin (hINV) mRNA level and promoter activity increase when keratinocytes are treated with the differentiating agent…