PITX2 gene

Known as: Otlx2, RS, paired like homeodomain 2 
This gene is involved in both the development of the pancreas and transcriptional regulation.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2018
0204019962018

Papers overview

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Highly Cited
2011
Highly Cited
2011
BACKGROUND Pitx2 is a homeobox transcription factor that plays a pivotal role in early left/right determination during embryonic… (More)
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2009
2009
PURPOSE Approximately 35% of patients with prostate cancer who undergo radical prostatectomy experience prostate specific antigen… (More)
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Highly Cited
2007
Highly Cited
2007
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in humans and is characterized by chaotic electrical… (More)
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2006
2006
PURPOSE PITX2 gene dose plays a central role in Axenfeld-Rieger syndrome. The purpose of this study was to test the hypothesis… (More)
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2002
2002
Three major PITX2 isoforms are differentially expressed in human, mice, zebrafish, chick, and frog tissues. To demonstrate… (More)
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Highly Cited
2002
Highly Cited
2002
"Early-onset glaucoma" refers to genetically heterogeneous conditions for which glaucoma manifests at age 5-40 years and for… (More)
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Highly Cited
2002
Highly Cited
2002
Analysis of an allelic series in mice revealed that the Pitx2 homeobox gene is required at multiple stages of pituitary… (More)
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2001
2001
The Rieger syndrome is an autosomal dominant disease characterized by ocular, craniofacial, and umbilical defects. Patients have… (More)
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2000
2000
The autosomal dominant disorders iris hypolasia (IH), iridogoniodysgenesis syndrome (IGDS) and Axenfeld-Rieger syndrome (ARS) are… (More)
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1998
1998
PURPOSE To determine whether autosomal dominant iris hypoplasia is caused by mutations in the newly described gene for Rieger… (More)
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