Axenfeld-Rieger Syndrome, Type 1

Known as: Rieger Syndrome Type 1, Rieger Syndrome, Type 1, RGS 
A rare autosomal dominant syndrome linked to mutations in the PITX2 gene. It is characterized by abnormalities in the anterior chamber of the eye and… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Stroke is a frequent cause of adult disability that can lead to enduring impairments. However, given the life-long plasticity of… (More)
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Review
2002
Review
2002
Regulators of G protein signaling (RGS) and RGS-like proteins are a family (>30 members) of highly diverse, multifunctional… (More)
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Highly Cited
2001
Highly Cited
2001
Complex defects in neuronal signaling may underlie the dysfunctions that characterize schizophrenia. Using cDNA microarrays, we… (More)
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Highly Cited
1999
Highly Cited
1999
G protein-coupled receptor kinases (GRKs) are well characterized regulators of G protein-coupled receptors, whereas regulators of… (More)
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Highly Cited
1998
Highly Cited
1998
Signaling by the Wnt family of extracellular proteins is critical in a variety of developmental processes in which cell and… (More)
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Highly Cited
1997
Highly Cited
1997
RGS proteins are GTPase activators for heterotrimeric G proteins. We report here the 2.8 A resolution crystal structure of the… (More)
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Highly Cited
1997
Highly Cited
1997
RGS proteins constitute a newly appreciated and large group of negative regulators of G protein signaling. Four members of the… (More)
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Highly Cited
1996
Highly Cited
1996
Rieger syndrome (REG) is an autosomal–dominant human disorder that includes anomalies of the anterior chamber of the eye, dental… (More)
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Highly Cited
1996
Highly Cited
1996
terized G protein GAP is phospholipase C-b, which is Summary both a GAP for Gqa and the effector that is activated by that G… (More)
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Highly Cited
1996
Highly Cited
1996
SIGNALLING pathways using heterotrimeric guanine-nucleotide-binding-proteins (G proteins) trigger physiological responses… (More)
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