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PITX1 gene

Known as: POTX, paired like homeodomain 1, PITUITARY HOMEOBOX 1 
National Institutes of Health

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Related topics

1 relation
homeobox protein PITX1

Papers overview

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Review
2018
Review
2018
A novel enhancer near the Pitx1 gene influences development and evolution of pelvic appendages in vertebrates
Vertebrate pelvic reduction is a classic example of repeated evolution. Recurrent loss of pelvic appendages in sticklebacks has… 
2012
2012
Conditional over-expression of PITX1 causes skeletal muscle dystrophy in mice
Summary Paired-like homeodomain transcription factor 1 (PITX1) was specifically up-regulated in patients with facioscapulohumeral… 
Highly Cited
2011
Highly Cited
2011
CpG island methylation profiling in human salivary gland adenoid cystic carcinoma
DNA methylation is a fundamental epigenetic event associated with physiologic and pathologic conditions, including cancer… 
Highly Cited
2007
Highly Cited
2007
Transcriptional activation of p53 by Pitx1
Little is known about factors that stimulate transcription of the p53 tumor suppressor gene. Here, we report that the human… 
Highly Cited
2007
Highly Cited
2007
Directional asymmetry of pelvic vestiges in threespine stickleback.
Extensive reduction of the size and complexity of the pelvic skeleton (i.e., pelvic reduction) has evolved repeatedly in… 
Highly Cited
2005
Highly Cited
2005
Activin regulates luteinizing hormone beta-subunit gene expression through Smad-binding and homeobox elements.
LH beta-subunit (LHbeta), which is essential for ovulation and reproductive fitness, is synthesized specifically in pituitary… 
Highly Cited
2003
Highly Cited
2003
Pitx1 and Pitx2 are required for development of hindlimb buds
Two closely related homeobox transcription factors, Pitx1 and Pitx2, have been implicated in patterning of lateral plate mesoderm… 
Highly Cited
2000
Highly Cited
2000
Antagonistic signals between BMP4 and FGF8 define the expression of Pitx1 and Pitx2 in mouse tooth-forming anlage.
Members of the Pitx/RIEG family of homeodomain-containing transcription factors have been implicated in vertebrate organogenesis… 
Highly Cited
1999
Highly Cited
1999
Role of Pitx1 upstream of Tbx4 in specification of hindlimb identity.
In spite of recent breakthroughs in understanding limb patterning, the genetic factors determining the differences between the… 
Highly Cited
1999
Highly Cited
1999
Pituitary Homeobox 1 (Ptx1) Is Differentially Expressed during Pituitary Development.
Pituitary homeobox 1 (Ptx1) is a homeodomain-containing transcription factor acting on transcription of all pituitary hormone… 
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