FAQ

PINX1 wt Allele

Known as: PIN2/TERF1 Interacting, Telomerase Inhibitor 1 wt Allele, LPTL, LPTS 
Human PINX1 wild-type allele is located in the vicinity of 8p23 and is approximately 74 kb in length. This allele, which encodes PIN2/TERF1… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1984-2017
012319842017

Related topics

Related topics

5 relations
Chromosome SegregationEnzyme InhibitionInhibition of Cell ProliferationMitotic Metaphase

Broader (1)

PINX1 gene

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
PINX1 wt Allele
Mitotic Metaphase
Chromosome Segregation
Inhibition of Cell Proliferation
PINX1 gene
Enzyme Inhibition

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
HIV-Tat-mediated delivery of an LPTS functional fragment inhibits telomerase activity and tumorigenicity of hepatoma cells.
BACKGROUND & AIMS Human liver-related putative tumor suppressor (LPTS) is a gene that encodes a telomerase inhibitory protein… (More)
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2010
2010
C-terminal amino acids 290-328 of LPTS/PinX1 confer telomerase inhibition.
LPTS/PinX1, a telomerase inhibitor composed of 328 amino acids, binds to the telomere associated protein Pin2/TRF1 and to the… (More)
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2008
2008
Identification of zebrafish LPTS: a gene with similarities to human LPTS/PinX1 that inhibits telomerase activity.
Human LPTS/PinX1 is a newly identified telomerase inhibitory protein. Overexpression of the LPTS/PinX1 gene suppresses telomerase… (More)
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2007
2007
Histological Analysis of the Lower-Positioned Transverse Ligament
The lower-positioned transverse ligament (LPTL) had been thought to run parallel to the junction between the orbital septum and… (More)
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2007
2007
[Preparation of a novel telomerase inhibitory protein LPTS-L].
The gene for LPTS is originally cloned as a human liver-related putative tumor suppressor (LPTS) gene that encodes a full length… (More)
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2003
2003
Mutation analysis of novel human liver-related putative tumor suppressor gene in hepatocellular carcinoma.
AIM To find the point mutations meaningful for inactivation of liver-related putative tumor suppressor gene (LPTS) gene, a human… (More)
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2002
2002
Genetic analysis of the liver putative tumor suppressor (LPTS) gene in hepatocellular carcinomas.
Recently, a novel liver-related putative tumor suppressor (LPTS), which has a growth inhibitory function in the hepatocellular… (More)
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2002
2002
Over-expression of LPTS-L in hepatocellular carcinoma cell line SMMC-7721 induces crisis.
AIM To evaluate the function of the longer transcripts LPTS-L in hepatocellular carcinoma cell line SMMC-7721. METHODS SMMC… (More)
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2002
2002
[The cloning and expression of a novel mouse gene mLPTS and its subcellular localization].
A novel mouse gene mLPTS was cloned by EST assembling, RT-PCR and DNA sequencing. The gene fragment for mLPTS is 1244 bp in… (More)
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2000
2000
Identification of the gene for a novel liver-related putative tumor suppressor at a high-frequency loss of heterozygosity region of chromosome 8p23 in human hepatocellular carcinoma.
Human chromosome 8p23 is known as a region that is associated with loss of heterozygosity (LOH), which is frequently deleted in… (More)
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