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PIM2 protein, human

Known as: PIM2, pim-2 oncogene protein, human, Serine/Threonine-Protein Kinase Pim-2 
Serine/threonine-protein kinase pim-2 (311 aa, ~34 kDa) is encoded by the human PIM2 gene. This protein plays a role in apoptosis regulation, protein… 
National Institutes of Health

Related topics

Related topics

16 relations
AutophagyCell Cycle ControlEnzyme GeneG1/S Transition Checkpoint

Broader (2)

Protein-Serine-Threonine KinasesProto-Oncogene Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Prosurvival kinase PIM2 is a therapeutic target for eradication of chronic myeloid leukemia stem cells
Significance Chronic myeloid leukemia (CML) is a hematopoietic cancer caused by the oncogenic fusion protein BCR-ABL. The first… 
2018
2018
A PIM-CHK1 signaling pathway regulates PLK1 phosphorylation and function during mitosis
ABSTRACT Although the kinase CHK1 is a key player in the DNA damage response (DDR), several studies have recently provided… 
2018
2018
PIM2 survival kinase is upregulated in a p53-dependent manner in cells treated with camptothecin or co-treated with actinomycin D and nutlin-3a.
2017
2017
Upregulation of PIM2 by Underexpression of MicroRNA-135-5p Improves Survival Rates of Skin Allografts by Suppressing Apoptosis of Fibroblast Cells
Background It has been reported that miR-135-5p is involved with many diseases. In this study, we aimed at define the… 
2015
2015
Validation of the Pediatric Index of Mortality 2 (PIM2) in Argentina: a prospective, multicenter, observational study.
INTRODUCTION The Pediatric Index of Mortality 2 (PIM2) is one of the most commonly used scoring systems to predict mortality in… 
2013
2013
Selecting the best mortality risk scoring systems in a PICU: a difficult decision.
The prognostic mortality scores are useful to assess the quality of care, compare the different services, scale professionals… 
2013
2013
Glycolysis in Cancer Cells Kinase M 2 ( PKM 2 ) and Promotes Pyruvate ( PIM 2 ) Oncogene Phosphorylates Proviral Insertion in Murine Lymphomas 2 Metabolism
2013
2013
Abstract 5194: Pim2 is required for maintaining Multiple Myeloma cell proliferation through modulating mTORC1 pathway.
Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC Multiple Myeloma (MM) is the second most common… 
2009
2009
SOCS3 expression induced by PIM2 requires PKC and PI3K signaling.
Highly Cited
1999
Highly Cited
1999
Structural study of the lipomannans from Mycobacterium bovis BCG: characterisation of multiacylated forms of the phosphatidyl-myo-inositol anchor.
A biosynthetic filiation is postulated between the mycobacterial phosphatidyl-myo-inositol mannosides (PIMs), the lipomannans… 
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