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PIM1 protein, human

Known as: Lon protease Pim1, human, c-pim-1 protein, human, pim-1 proto-oncogene protein, human 
Serine/threonine-protein kinase pim-1 (404 aa, ~45 kDa) is encoded by the human PIM1 gene. This protein plays a role in both cell proliferation and… Expand
National Institutes of Health

Papers overview

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Review
2010
Review
2010
The highly conserved proto-oncogenic protein PIM1 is an unusual serine or threonine kinase, in part because it is constitutively… Expand
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Highly Cited
2009
Highly Cited
2009
BackgroundThe serine/threonine kinase PIM1 has been implicated as an oncogene in various human cancers including lymphomas… Expand
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Highly Cited
2009
Highly Cited
2009
PIM1 is a serine /threonine kinase that has diverse biological roles in cell survival, proliferation and differentiation. PIM1… Expand
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Highly Cited
2009
Highly Cited
2009
FLT3-ITD–mediated leukemogenesis is associated with increased expression of oncogenic PIM serine/threonine kinases. To dissect… Expand
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Highly Cited
2008
Highly Cited
2008
The contribution of basophils in allergic disease and other Th2-type immune responses depends on their persistence at sites of… Expand
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Highly Cited
2007
Highly Cited
2007
The serine/threonine kinase human Pim1 (hereafter PIM1) cooperates with human c-Myc (hereafter MYC) in cell cycle progression and… Expand
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Highly Cited
2007
Highly Cited
2007
The pim-1 kinase is a true oncogene that has been implicated in the development of leukemias, lymphomas, and prostate cancer, and… Expand
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Highly Cited
2002
Highly Cited
2002
BCR/ABL oncogenic tyrosine kinase activates STAT5, which plays an important role in leukemogenesis. The downstream effectors of… Expand
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Highly Cited
1994
Highly Cited
1994
ATP dependent proteolytic degradation of misfolded proteins in the mitochondrial matrix is mediated by the PIM1 protease and… Expand
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Highly Cited
1994
Highly Cited
1994
The PIM1 nuclear gene in the yeast Saccharomyces cerevisiae encodes a mitochondrial ATP-dependent protease that exhibits over 30… Expand
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