PIM1 protein, human

Known as: Lon protease Pim1, human, c-pim-1 protein, human, pim-1 proto-oncogene protein, human 
Serine/threonine-protein kinase pim-1 (404 aa, ~45 kDa) is encoded by the human PIM1 gene. This protein plays a role in both cell proliferation and… (More)

Topic mentions per year

Topic mentions per year

1994-2018
05101519942018

Papers overview

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2012
2012
Patients with acute myeloid leukemia (AML) and a FLT3 internal tandem duplication (ITD) mutation have a poor prognosis, and FLT3… (More)
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Highly Cited
2010
Highly Cited
2010
The oncogenic PIM1 kinase has been implicated as a cofactor for c-MYC in prostate carcinogenesis. In this study, we show that in… (More)
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2009
2009
The serine/threonine kinase PIM1 has been implicated as an oncogene in various human cancers including lymphomas, gastric… (More)
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Highly Cited
2009
Highly Cited
2009
FLT3-ITD-mediated leukemogenesis is associated with increased expression of oncogenic PIM serine/threonine kinases. To dissect… (More)
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2009
2009
The serine/threonine kinase, PIM1, is involved in promoting cell survival in part by phosphorylation and inhibition of… (More)
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Highly Cited
2008
Highly Cited
2008
CK2 (casein kinase 2) is a very pleiotropic serine/threonine protein kinase whose abnormally high constitutive activity has often… (More)
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Highly Cited
2007
Highly Cited
2007
The serine/threonine kinase human Pim1 (hereafter PIM1) cooperates with human c-Myc (hereafter MYC) in cell cycle progression and… (More)
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2007
2007
The pim-1 kinase is a true oncogene that has been implicated in the development of leukemias, lymphomas, and prostate cancer, and… (More)
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Highly Cited
2001
Highly Cited
2001
Genomic instability promotes tumorigenesis and can occur through various mechanisms, including defective segregation of… (More)
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1994
1994
ATP dependent proteolytic degradation of misfolded proteins in the mitochondrial matrix is mediated by the PIM1 protease and… (More)
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