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PIK3R4 gene

Known as: p150, phosphoinositide-3-kinase regulatory subunit 4, PIK3R4 
National Institutes of Health

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PIK3R3 gene

Papers overview

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2019
2019
Phosphorylation of BECLIN-1 by BCR-ABL suppresses autophagy in chronic myeloid leukemia
Autophagy is a genetically regulated process of adaptation to metabolic stress and was recently shown to be involved in the… 
2019
2019
Vps15 is critical to mediate autophagy in AngII treated HUVECs probably by PDK1/PKC signaling pathway.
2018
2018
Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans
The formation of the vertebrate brain requires the generation, migration, differentiation and survival of neurons. Genetic… 
2018
2018
TbVps15 is required for vesicular transport and cytokinesis in Trypanosoma brucei.
2017
2017
Vps15p regulates the distribution of cup‐shaped organelles containing the major eisosome protein Pil1p to the extracellular fraction required for endocytosis of extracellular vesicles carrying…
Exosomes are small vesicles secreted from virtually every cell from bacteria to humans. Saccharomyces cerevisiae is a model… 
Highly Cited
2016
Highly Cited
2016
Characterization of Atg38 and NRBF2, a fifth subunit of the autophagic Vps34/PIK3C3 complex
ABSTRACT The phosphatidylinositol 3-kinase Vps34 is part of several protein complexes. The structural organization of… 
2015
2015
High expression of PI3K core complex genes is associated with poor prognosis in chronic lymphocytic leukemia.
2014
2014
Vps15 is required for stress induced and developmentally triggered autophagy and salivary gland protein secretion in Drosophila
Autophagy is a catabolic process used to deliver cellular material to the lysosome for degradation. The core Vps34/class III… 
2008
2008
Pdr5-mediated multidrug resistance requires the CPY-vacuolar sorting protein Vps3: are xenobiotic compounds routed from the vacuole to plasma membrane transporters for efflux?
In Saccharomyces cerevisiae several members of the ATP-binding cassette transporter superfamily efflux a broad range of… 
Highly Cited
1995
Highly Cited
1995
Vesicle-mediated protein transport: regulatory interactions between the Vps15 protein kinase and the Vps34 PtdIns 3-kinase essential for protein sorting to the vacuole in yeast
A membrane-associated complex composed of the Vps15 protein kinase and the Vps34 phosphatidylinositol 3-kinase (PtdIns 3-kinase… 
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