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PIK3C3 wt Allele
Known as:
VPS34, Yeast, Homolog of Gene
, VPS34
, Phosphatidylinositol 3-Kinase, Catalytic Subunit Type 3 wt Allele
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Human PIK3C3 wild-type allele is located in the vicinity of 18q12.3 and is approximately 133 kb in length. This allele, which encodes…
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National Institutes of Health
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Related topics
Related topics
9 relations
Autophagy
Autophagy Regulation Pathway
Cytokinesis
Immune response
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Protective effects of resveratrol on random-pattern skin flap survival: an experimental study.
Jinti Lin
,
Renjin Lin
,
+10 authors
Kailiang Zhou
American journal of translational research
2019
Corpus ID: 73477992
Random-pattern skin flap transplantation is a common procedure in plastic surgery, but its distal area usually incurs ischemia…
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2019
2019
Critical Role for Phosphatidylinositol-3 Kinase Vps34/PIK3C3 in ON-Bipolar Cells
F. He
,
R. Nichols
,
Lavanya Kailasam
,
T. Wensel
,
Melina A. Agosto
Investigative Ophthalmology and Visual Science
2019
Corpus ID: 195757137
Purpose Phosphatidylinositol-3-phosphate (PI(3)P), and Vps34, the type III phosphatidylinositol 3-kinase primarily responsible…
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2015
2015
Class III PI 3-kinase is the main source of PtdIns3P substrate and membrane recruitment signal for PIKfyve constitutive function in podocyte endomembrane homeostasis.
O. Ikonomov
,
D. Sbrissa
,
M. Venkatareddy
,
E. Tisdale
,
P. Garg
,
A. Shisheva
Biochimica et Biophysica Acta
2015
Corpus ID: 43430226
2015
2015
Blockade of Emodin on Amyloid-β 25–35-Induced Neurotoxicity in AβPP/PS1 Mice and PC12 Cells through Activation of the Class III Phosphatidylinositol 3-Kinase/Beclin-1/B-Cell Lymphoma 2 Pathway
Yan-ping Sun
,
Ji-ping Liu
Planta Medica
2015
Corpus ID: 29413475
Abstract Autophagy plays an important role in the pathogenesis of Alzheimerʼs disease. In the present study, the blockade…
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2014
2014
Resistance to Inhibitors of Cholinesterase (Ric)-8A and Gαi Contribute to Cytokinesis Abscission by Controlling Vacuolar Protein-Sorting (Vps)34 Activity
C. Boularan
,
Olena Kamenyeva
,
Hyeseong Cho
,
J. Kehrl
PLoS ONE
2014
Corpus ID: 2642017
Resistance to inhibitors of cholinesterase (Ric)-8A is a guanine nucleotide exchange factor for Gαi, Gαq, and Gα12/13, which is…
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2014
2014
Autophagic induction of amyotrophic lateral sclerosis-linked Cu/Zn superoxide dismutase 1 G93A mutant in NSC34 cells
Yanming Wei
Neural Regeneration Research
2014
Corpus ID: 7797320
Previous studies have confirmed that the beclin 1 complex plays a key role in the initial stage of autophagy and deregulated…
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2012
2012
Vps34p Is Required for the Decline of Extracellular Fructose-1,6-bisphosphatase in the Vacuole Import and Degradation Pathway*
Abbas A Alibhoy
,
Bennett J. Giardina
,
Danielle D Dunton
,
H. Chiang
Journal of Biological Chemistry
2012
Corpus ID: 46132985
Background: Gluconeogenic enzymes are degraded in the vacuole via the Vid pathway during glucose re-feeding. Results: Fructose-1…
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2011
2011
Astrocyte elevated gene-1 activates AMPK in response to cellular metabolic stress and promotes protective autophagy
S. Bhutia
,
T. Kegelman
,
+5 authors
P. Fisher
Autophagy
2011
Corpus ID: 36855336
Although autophagy can function as a tumor-suppression mechanism, recent studies provide compelling evidence that during cancer…
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2010
2010
pp60c-Src phosphorylates and activates vacuolar protein sorting 34 to mediate cellular transformation.
D. Hirsch
,
Yi Shen
,
Milos Dokmanovic
,
W. J. Wu
Cancer Research
2010
Corpus ID: 16416222
Vacuolar protein sorting 34 (VPS34) contributes to the regulation of the mammalian target of rapamycin complex 1/S6 kinase 1…
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2008
2008
A VAST staging area for regulatory proteins
A. Mitchell
Proceedings of the National Academy of Sciences…
2008
Corpus ID: 19908947
The vesicle trafficking system has long been known to influence signal transduction through its role in biogenesis and…
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