PIK3C3 wt Allele

Known as: VPS34, Yeast, Homolog of Gene, VPS34, Phosphatidylinositol 3-Kinase, Catalytic Subunit Type 3 wt Allele 
Human PIK3C3 wild-type allele is located in the vicinity of 18q12.3 and is approximately 133 kb in length. This allele, which encodes… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2017
0102019902017

Papers overview

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Highly Cited
2013
Highly Cited
2013
Autophagy is the primary cellular catabolic program activated in response to nutrient starvation. Initiation of autophagy… (More)
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Highly Cited
2011
Highly Cited
2011
Autophagy normally involves the formation of double-membrane autophagosomes that mediate bulk cytoplasmic and organelle… (More)
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Highly Cited
2005
Highly Cited
2005
The plant innate immune response includes the hypersensitive response (HR), a form of programmed cell death (PCD). PCD must be… (More)
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Highly Cited
2002
Highly Cited
2002
A direct role for phosphoinositides in vesicular trafficking has been demonstrated by the identification of the yeast VPS34 gene… (More)
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Highly Cited
2001
Highly Cited
2001
Phagosomes acquire their microbicidal properties by fusion with lysosomes. Products of phosphatidylinositol 3-kinase (PI 3-kinase… (More)
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Highly Cited
2001
Highly Cited
2001
After internalization from the plasma membrane, activated EGF receptors (EGFRs) are delivered to multivesicular bodies (MVBs… (More)
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Highly Cited
2000
Highly Cited
2000
Myotubular myopathy (MTM1) is an X-linked disease, characterized by severe neonatal hypotonia and generalized muscle weakness… (More)
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Highly Cited
1993
Highly Cited
1993
The yeast TOR2 gene encodes an essential 282 kd phosphatidylinositol (PI) 3-kinase homolog. TOR2 is related to the catalytic… (More)
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Highly Cited
1993
Highly Cited
1993
The VPS34 gene product (Vps34p) is required for protein sorting to the lysosome-like vacuole of the yeast Saccharomyces… (More)
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Highly Cited
1990
Highly Cited
1990
VPS34 gene function is required for the efficient localization of a variety of vacuolar proteins. We have cloned and sequenced… (More)
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