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PI103

Known as: PI 103, PI-103 
National Institutes of Health

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3 relations

Broader (3)

FuransPyridinesPyrimidines

Papers overview

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2019
2019
Novel chemotherapeutic agent, FND-4b, activates AMPK and inhibits colorectal cancer cell proliferation
Colorectal cancer (CRC) is the second leading cause of cancer deaths in the US with the majority of deaths due to metastatic… 
2017
2017
In vitro nuclear magnetic resonance spectroscopy metabolic biomarkers for the combination of temozolomide with PI3K inhibition in paediatric glioblastoma cells
Recent experimental data showed that the PI3K pathway contributes to resistance to temozolomide (TMZ) in paediatric glioblastoma… 
2015
2015
Role of phosphoinositide 3-kinase IA (PI3K-IA) activation in cardioprotection induced by ouabain preconditioning.
2015
2015
Overexpression of PI3K p110α contributes to acquired resistance to MET inhibitor, in MET-amplified SNU-5 gastric xenografts
Gastric cancer is one of the most virulent malignant diseases and is the second leading cause of cancer mortality in the world… 
2013
2013
Molecular and Cellular Pathobiology FOXO 3 a Is a Major Target of Inactivation by PI 3 K / AKT Signaling in Aggressive Neuroblastoma
Neuroblastoma is a pediatric tumor of the peripheral sympathetic nervous system with a highly variable prognosis. Activation of… 
2013
2013
PI-103 sensitizes acute myeloid leukemia stem cells to daunorubicin-induced cytotoxicity
To date, acute myeloid leukemia (AML) shows very poor outcome for conventional chemotherapy. Leukemia stem cells (LSCs) are… 
2012
2012
A Yeast-Based In Vivo Bioassay to Screen for Class I Phosphatidylinositol 3-Kinase Specific Inhibitors
The phosphatidylinositol 3-kinase (PI3K) pathway couples receptor-mediated signaling to essential cellular functions by… 
2011
2011
Obesity, insulin and chemoresistance in colon cancer.
Obesity, a condition characterised by chronic hyperinsulinemia, is a firmly established risk factor for incident colon cancer (1… 
2010
2010
Quantitative analysis of tumor vascular structure after drug treatment
This paper reports a method that aims to quantify the changes of tumour vascular structure as a result of drug treatment. The… 
Highly Cited
2008
Highly Cited
2008
Genetic or pharmaceutical blockade of p110delta phosphoinositide 3-kinase enhances IgE production.
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