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PI103

Known as: PI 103, PI-103 
 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Combined inhibition of PI3K, mTOR, and autophagy promotes glioma cell death. Blocking All Escape Routes Many cancers, including… Expand
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Review
2010
Review
2010
The phosphatidylinositide 3-kinase (PI3K) pathway is very commonly activated in a wide range of human cancers and is a major… Expand
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Highly Cited
2010
Highly Cited
2010
Targeting the mammalian target of rapamycin (mTOR) protein is a promising strategy for cancer therapy. The mTOR kinase functions… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Aberrant Ras/Raf/MAPK and PI3K/AKT/mTOR signaling pathways are found in hepatocellular carcinoma (HCC). This study… Expand
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Highly Cited
2009
Highly Cited
2009
The phosphatidylinositide 3-kinase pathway is frequently deregulated in human cancers and inhibitors offer considerable… Expand
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Highly Cited
2009
Highly Cited
2009
Phosphoinositide 3-kinases (PI3Ks) are among the most frequently activated signaling pathways in cancer. In chronic lymphocytic… Expand
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Highly Cited
2008
Highly Cited
2008
Cell signaling initiated at the epidermal growth factor receptor (EGFR), RAS oncoproteins, or PI3K contributes to a common… Expand
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Highly Cited
2008
Highly Cited
2008
The phosphatidylinositol 3-kinase (PI3K)/Akt and mammalian target of rapamycin complex 1 (mTORC1) signaling pathways are… Expand
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Highly Cited
2007
Highly Cited
2007
We have shown previously that blockade of epidermal growth factor receptor (EGFR) cooperates with a pan-selective inhibitor of… Expand
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Highly Cited
2006
Highly Cited
2006
The PI3 kinase family of lipid kinases promotes cell growth and survival by generating the second messenger phosphatidylinositol… Expand
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