FAQ

PGF wt Allele

Known as: D12S1900, Placental Growth Factor wt Allele, PlGF 
Human PGF wild-type allele is located within 14q24-q31 and is approximately 14 kb in length. This allele, which encodes placenta growth factor… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1972-2018
0204019722018

Related topics

Related topics

14 relations
14q24-q31Angiogenic ProcessCell Proliferation Regulatory ProcessFocal adhesion pathway
(More)

Broader (1)

PGF gene

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
PGF wt Allele
Migration, Cell
Homo sapiens
receptor binding
Intercellular Communication Process
PGF gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Predictive Value of the sFlt-1:PlGF Ratio in Women with Suspected Preeclampsia.
BACKGROUND The ratio of soluble fms-like tyrosine kinase 1 (sFlt-1) to placental growth factor (PlGF) is elevated in pregnant… (More)
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Highly Cited
2011
Highly Cited
2011
Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab
Pharmacological inhibition of VEGF-A has proven to be effective in inhibiting angiogenesis and vascular leak associated with… (More)
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Highly Cited
2010
Highly Cited
2010
Prospective study of placental angiogenic factors and maternal vascular function before and after preeclampsia and gestational hypertension.
BACKGROUND Preeclampsia is a life-threatening pregnancy syndrome of uncertain origin. To elucidate the pathogenesis, we evaluated… (More)
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Highly Cited
2009
Highly Cited
2009
A prospective cohort study of the value of maternal plasma concentrations of angiogenic and anti-angiogenic factors in early pregnancy and midtrimester in the identification of patients destined to…
OBJECTIVE Changes in the maternal plasma concentrations of angiogenic (placental growth factor (PlGF) and vascular endothelial… (More)
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Highly Cited
2007
Highly Cited
2007
Circulating protein biomarkers of pharmacodynamic activity of sunitinib in patients with metastatic renal cell carcinoma: modulation of VEGF and VEGF-related proteins
Sunitinib malate (SUTENT®) is an oral, multitargeted tyrosine kinase inhibitor, approved multinationally for the treatment of… (More)
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Highly Cited
2005
Highly Cited
2005
Urinary placental growth factor and risk of preeclampsia.
CONTEXT Preeclampsia may be caused by an imbalance of angiogenic factors. We previously demonstrated that high serum levels of… (More)
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Highly Cited
2005
Highly Cited
2005
Soluble fms-like tyrosine kinase 1 is increased in preeclampsia but not in normotensive pregnancies with small-for-gestational-age neonates: relationship to circulating placental growth factor.
CONTEXT An excess of the soluble receptor, fms-like tyrosine kinase 1 (sFlt-1) may contribute to maternal vascular dysfunction in… (More)
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Highly Cited
2004
Highly Cited
2004
Circulating Angiogenic Factors and the Risk of Preeclampsia in Systemic Lupus Erythematosus Pregnancies.
OBJECTIVE To investigate whether angiogenic factors are associated with risk of developing preeclampsia in pregnant women with… (More)
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Highly Cited
2003
Highly Cited
2003
VEGFR-1-selective VEGF homologue PlGF is arteriogenic: evidence for a monocyte-mediated mechanism.
Two signaling receptors for vascular endothelial growth factor (VEGF) in the vasculature are known with not yet well-understood… (More)
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Highly Cited
2003
Highly Cited
2003
Clinical risk factors for primary graft failure following lung transplantation.
STUDY OBJECTIVE s: Primary graft failure (PGF) is a devastating acute lung injury syndrome following lung transplantation. We… (More)
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