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A controlled trial of antepartum glucocorticoid treatment for prevention of the respiratory distress syndrome in premature infants.
Preliminary evidence justifies further trials, but that further work is needed before any new routine procedure is established, as there may be an increased risk of fetal death in pregnancies complicated by severe hypertensionedema-proteinuria syndromes and treated with betamethasone. Expand
The role of cortisol in preparing the fetus for birth.
  • G. Liggins
  • Biology, Medicine
  • Reproduction, fertility, and development
  • 1994
The glucocorticoids, cortisol and corticosterone, have a unique function in the fetus in inducing a wide range of enzymes before birth that have little or no function during fetal life but on whichExpand
Hemoglobin concentrations and blood gas tensions of free-diving Weddell seals.
It is suggested that an extension of the sympathetic outflow of the diving reflex possibly caused profound contraction of the Weddell seal's very large spleen (0.89% of body wt at autopsy), although the authors have no direct evidence. Expand
Regional blood flow during simulated diving in the conscious Weddell seal.
It is concluded that blood flow during diving is directed to organs and tissues according to their metabolic requirements. Expand
Seal lungs collapse during free diving: evidence from arterial nitrogen tensions.
In a single dive, alveolar collapse and redistribution of blood nitrogen allow the seal to avoid nitrogen narcosis and decompression sickness. Expand
Heart rate and body temperature during free diving of Weddell seals.
The first microprocessor-controlled monitors for collection of data on depth, heart rate, and body temperature of one fetal and five adult male freely swimming Weddell seals are developed and successfully used. Expand
Premature delivery of foetal lambs infused with glucocorticoids.
  • G. Liggins
  • Biology, Medicine
  • The Journal of endocrinology
  • 1 December 1969
Parturition induced by dexamethasone was not delayed by administration of 100 mg. Expand
Microcomputer-assisted metabolic studies of voluntary diving of Weddell seals.
Utilizing a microprocessor-controlled peristaltic withdrawal pump, arterial blood samples were obtained from Weddell seals (Leptonychotes weddelli) while diving voluntarily under the sea ice atExpand
The mechanism of initiation of parturition in the ewe.
The chapter explains that the concentration of total unconjugated estrogen in the peripheral plasma of pregnant sheep is low and the acute effect of estrogen on uterine smooth muscle in vitro is usually inhibitory and its stimulatory action in vivo is the result of the release of an oxytocic material. Expand
Splenic contraction, catecholamine release, and blood volume redistribution during diving in the Weddell seal.
The spleen of the Weddell seal (Leptonychotes weddelli) may contract and inject red blood cells (RBCs) into the peripheral circulation during diving, but evidence for this hypothesis is indirect.Expand