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PF 8380

Known as: PF-8380, PF8380 
 
National Institutes of Health

Papers overview

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2019
2019
Obesity is associated with increased cardiovascular morbidity and mortality, but the direct signals to initiate or exaggerate… Expand
2018
2018
Idiopathic pulmonary fibrosis (IPF) is a chronic fibrosing lung disease with a dismal prognosis and a largely unknown etiology… Expand
2018
2018
Abstract Lysophosphatidic acid (LPA) is a simple biological lipid and mediates several biological functions with LPA receptors… Expand
2018
2018
Crohn's disease (CD) is a chronic, relapsing, inflammatory disease that is often associated with malnutrition because of… Expand
2017
2017
The autotaxin-lysophophatidic acid (ATX-LPA) signaling pathway is involved in several human diseases such as cancer, autoimmune… Expand
2016
2016
BackgroundThe lysophospholipids sphingosine-1-phosphate (S1P) and lysophosphatidic acid (LPA) are pleiotropic signaling molecules… Expand
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2015
2015
We previously reported that i) a Western diet increased levels of unsaturated lysophosphatidic acid (LPA) in small intestine and… Expand
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2013
2013
Purpose: Glioblastoma multiforme (GBM) is an aggressive primary brain tumor that is radio-resistant and recurs despite aggressive… Expand
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2013
2013
A series of PF‐8380 analogs, a recently developed autotaxin inhibitor, was explored. Inhibition of autotaxin by these analogs, as… Expand
Highly Cited
2010
Highly Cited
2010
Autotaxin is the enzyme responsible for the production of lysophosphatidic acid (LPA) from lysophosphatidyl choline (LPC), and it… Expand
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