PF 8380

Known as: PF-8380, PF8380 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2010-2017
012320102017

Papers overview

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2017
2017
Autotaxin (ATX) is an adipokine that generates the bioactive lipid, lysophosphatidic acid. Despite recent studies implicating… (More)
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2017
2017
The autotaxin-lysophophatidic acid (ATX-LPA) signaling pathway is involved in several human diseases such as cancer, autoimmune… (More)
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2017
2017
In an effort to find new therapeutic interventions addressing the unmet medical need of patients with idiopathic pulmonary… (More)
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2016
2016
The lysophospholipids sphingosine-1-phosphate (S1P) and lysophosphatidic acid (LPA) are pleiotropic signaling molecules with a… (More)
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2015
2015
We previously reported that i) a Western diet increased levels of unsaturated lysophosphatidic acid (LPA) in small intestine and… (More)
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2013
2013
PURPOSE Glioblastoma multiforme (GBM) is an aggressive primary brain tumor that is radio-resistant and recurs despite aggressive… (More)
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2013
2013
A series of PF-8380 analogs, a recently developed autotaxin inhibitor, was explored. Inhibition of autotaxin by these analogs, as… (More)
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2010
2010
Autotaxin is the enzyme responsible for the production of lysophosphatidic acid (LPA) from lysophosphatidyl choline (LPC), and it… (More)
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