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PF 573228

Known as: PF-573228, PF573228, PF 573,228 
National Institutes of Health

Papers overview

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2019
2019
Depletion of Host Cell Focal Adhesion Kinase Increases the Susceptibility to Invasion by Trypanosoma cruzi Metacyclic Forms
Focal adhesion kinase (FAK), a cytoplasmic protein tyrosine kinase (PTK), is implicated in diverse cellular processes, including… 
2019
2019
Increased intracellular Cl- concentration by activating FAK promotes airway epithelial BEAS-2B cells proliferation and wound healing.
2016
2016
PF573,228 inhibits vascular tumor cell growth, migration as well as angiogenesis, induces apoptosis and abrogates PRAS40 and S6RP phosphorylation
Abstract PF573,228 is a compound that targets focal adhesion kinase (FAK), a non-receptor protein kinase, which is over-expressed… 
2015
2015
Osmotic shrinkage elicits FAK- and Src phosphorylation and Src-dependent NKCC1 activation in NIH3T3 cells.
The mechanisms linking cell volume sensing to volume regulation in mammalian cells remain incompletely understood. Here, we test… 
2015
2015
Inhibitory actions by ibandronate sodium, a nitrogen-containing bisphosphonate, on calcium-activated potassium channels in Madin–Darby canine kidney cells
2015
2015
Abstract 423: CXCL12/CXCR4 activation by cancer-associated fibroblasts promotes integrin β1 clustering and invasive ability in gastric cancer
Purpose: Gastric cancer (GC) is the fourth most commonly diagnosed cancer and the third leading cause of cancer mortality… 
2014
2014
The involvement of FAK and Src in the invasion of cardiomyocytes by Trypanosoma cruzi.
2013
2013
Off‐targets effects underlie the inhibitory effect of FAK inhibitors on platelet activation: studies using Fak‐deficient mice
Focal adhesion kinase (FAK) is a non-receptor protein tyrosine kinase critical in mediating adhesion and migration in many cell… 
2013
2013
Focal Adhesion Kinase Regulates Collagen I–Induced Airway Smooth Muscle Phenotype Switching
Increased extracellular matrix (ECM) deposition and airway smooth muscle (ASM) mass are major contributors to airway remodeling… 
2009
2009
Characterization of a novel focal adhesion kinase inhibitor in human platelets
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