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Physiology of cell volume regulation in vertebrates.
The ability to control cell volume is pivotal for cell function. Cell volume perturbation elicits a wide array of signaling events, leading to protective (e.g., cytoskeletal rearrangement) andExpand
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Membrane mechanisms and intracellular signalling in cell volume regulation.
Recent work on selected aspects of the cellular and molecular physiology of cell volume regulation is reviewed. First, the physiological significance of the regulation of cell volume is discussed.Expand
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PDGFRalphaalpha signaling is regulated through the primary cilium in fibroblasts.
Recent findings show that cilia are sensory organelles that display specific receptors and ion channels, which transmit signals from the extracellular environment via the cilium to the cell toExpand
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Membrane mechanisms in volume and pH regulation in vertebrate cells.
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PDGFRαα Signaling Is Regulated through the Primary Cilium in Fibroblasts
Recent findings show that cilia are sensory organelles that display specific receptors and ion channels, which transmit signals from the extracellular environment via the cilium to the cell toExpand
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TMEM16F (Anoctamin 6), an anion channel of delayed Ca2+ activation
Members of the TMEM16 (Anoctamin) family of membrane proteins have been shown to be essential constituents of the Ca2+-activated Cl− channel (CaCC) in many cell types. In this study, we haveExpand
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Directional Cell Migration and Chemotaxis in Wound Healing Response to PDGF-AA are Coordinated by the Primary Cilium in Fibroblasts
Cell motility and migration play pivotal roles in numerous physiological and pathophysiological processes including development and tissue repair. Cell migration is regulated through external stimuliExpand
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The cytoskeleton and cell volume regulation.
Although the precise mechanisms have yet to be elucidated, early events in osmotic signal transduction may involve the clustering of cell surface receptors, initiating downstream signaling eventsExpand
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Advances in Comparative and Environmental Physiology
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Hypotonic shock mediation by p38 MAPK, JNK, PKC, FAK, OSR1 and SPAK in osmosensing chloride secreting cells of killifish opercular epithelium
SUMMARY Hypotonic shock rapidly inhibits Cl- secretion by chloride cells, an effect that is osmotic and not produced by NaCl-depleted isosmotic solutions, yet the mechanism for the inhibition and itsExpand
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