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PF-04418948
National Institutes of Health
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2020
2020
EP2 Receptor Blockade Attenuates COX-2 Upregulation During Intestinal Inflammation.
J. Golden
,
L. Illingworth
,
+10 authors
H. Ford
Shock
2020
Corpus ID: 201844951
High levels of PGE2 have been implicated in the pathogenesis of intestinal inflammatory disorders such as necrotizing…
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2017
2017
Signaling pathway involved in the inhibitory effect of FTY720P on the Na+/K+ ATPase in HepG2 cells
Nadine Al Alam
,
S. Kreydiyyeh
Journal of cell communication and signaling
2017
Corpus ID: 23745332
The Na+/K+ ATPase modulates the activity of many transporters in the liver, and maintains the ionic constancy of the…
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2016
2016
Role of EP2 and EP4 receptors in airway microvascular leak induced by prostaglandin E2
Victoria C Jones
,
M. Birrell
,
+5 authors
M. Belvisi
British Journal of Pharmacology
2016
Corpus ID: 13920629
Airway microvascular leak (MVL) involves the extravasation of proteins from post‐capillary venules into surrounding tissue. MVL…
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2016
2016
Pulmonary , gastrointestinal and urogenital pharmacology Prostaglandin E 2 induces expression of MAPK phosphatase 1 ( MKP-1 ) in airway smooth muscle cells
2016
Corpus ID: 207772798
Prostaglandin E2 (PGE2) is a prostanoid with diverse actions in health and disease. In chronic respiratory diseases driven by…
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2015
2015
Challenge with hyperosmolar mannitol induces mast cell activation in isolated human small airways : a model of exercise-induced bronchoconstriction
J. Säfholm
,
M. Adner
2015
Corpus ID: 53529885
A protocol was developed to investigate hyperosmolar mannitol-induced bronchoconstriction (Emax: 43.0 ± 3.2%). The constriction…
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2015
2015
EP2 Receptor Antagonist PF-04418948 Blocks Prostaglandin E2-Induction of Cyclooxygenase-2 and Decreases the Incidence of Experimental Necrotizing Enterocolitis
J. Golden
,
Patil Kavarian
,
+7 authors
H. Ford
2015
Corpus ID: 74335826
2014
2014
Possible involvement of brain prostaglandin E2 and prostanoid EP3 receptors in prostaglandin E2 glycerol ester-induced activation of central sympathetic outflow in the rat
Takahiro Shimizu
,
Kenjiro Tanaka
,
+8 authors
M. Saito
Neuropharmacology
2014
Corpus ID: 37184856
2014
2014
Role of prostaglandins in spinal transmission of the exercise pressor reflex in decerebrated rats
A. Stone
,
Steven W Copp
,
Marc P. Kaufman
Neuroscience
2014
Corpus ID: 24809406
2014
2014
Antifibrotic Effects of Noscapine through Activation of Prostaglandin E2 Receptors and Protein Kinase A*
Jacob Kach
,
N. Sandbo
,
+6 authors
N. Dulin
Journal of Biological Chemistry
2014
Corpus ID: 24738773
Background: Noscapine is a safe orally available anticough medicine also known to bind microtubules and induce cancer cell death…
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2014
2014
Sa1983 Radial Partitioning of the Gut Microbiota Associated With Tolerance to Oxygen and Asaccharolytic Metabolism
L. Albenberg
,
T. Esipova
,
+9 authors
Gary D. Wu
2014
Corpus ID: 57333445
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