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PF-00547659

National Institutes of Health

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1 relation

Broader (1)

Antibodies, Monoclonal, Humanized

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Anti-MAdCAM-1 antibody (PF-00547659) for active refractory Crohn’s disease in Japanese and Korean patients: the OPERA study
Background/Aims PF-00547659 is a monoclonal antibody against human mucosal addressin cell adhesion molecule-1 (MAdCAM-1) that… 
Review
2019
Review
2019
Rational and clinical development of the anti-MAdCAM monoclonal antibody for the treatment of IBD
ABSTRACT Introduction: Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) expression in gut-associated lymphoid tissue is… 
2017
2017
Anti-MAdCAM Antibody Increases ß7+ T Cells and CCR9 Gene Expression in the Peripheral Blood of Patients With Crohn’s Disease
Abstract Objective To define pharmacodynamic biomarkers in the peripheral blood of patients with Crohn’s disease [CD] after… 
2017
2017
Normal intrathecal leukocyte cell number and composition do not decrease the incidence of post–lumbar puncture headache
2017
2017
Therapy: Bacteriophages important for FMT efficacy
  • Iain Dickson
  • Nature Reviews Gastroenterology &Hepatology
  • 2017
  • Corpus ID: 43196827
2017
2017
IBD: Phase II trial success for anti-MADCAM1 antibody
  • Iain Dickson
  • Nature Reviews Gastroenterology &Hepatology
  • 2017
  • Corpus ID: 12276576
2015
2015
901a A Randomized, Multicenter Double-Blind, Placebo-Controlled Study of the Safety and Efficacy of Anti-MAdCAM Antibody PF-00547659 (PF) in Patients With Moderate to Severe Ulcerative Colitis…
2014
2014
Targeting of gut specific leucocyte recruitment in IBD by vedolizumab
IBD is characterised by an inappropriate immune response to our own gut microbiota in the setting of a genetically susceptible… 
2013
2013
The TOSCA Study of Immune Surveillance in Cerebrospinal Fluid (CSF) in Crohnʼs Disease (CD) Patients Treated with Anti-MAdCAM Monoclonal Antibody (MAb) PF-00547659: Cohort 1 Clinical Results: 1750
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