PEBP1 gene

Known as: RKIP, hippocampal cholinergic neurostimulating peptide, PEBP 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1979-2018
0204019792018

Papers overview

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Highly Cited
2006
Highly Cited
2006
BACKGROUND Diminished expression of Raf kinase inhibitor protein (RKIP), an inhibitor of the Raf signaling cascade, promotes… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND & AIMS The Raf kinase inhibitor protein (RKIP) has been identified as a suppressor of the mitogen-activated protein… (More)
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Highly Cited
2005
Highly Cited
2005
PURPOSE Raf-1 kinase inhibitor protein (RKIP) was originally identified as the first physiologic inhibitor of the Raf/mitogen… (More)
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Highly Cited
2004
Highly Cited
2004
Cancer cells are more susceptible to chemotherapeutic agent-induced apoptosis than their normal counterparts. Although it has… (More)
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Highly Cited
2004
Highly Cited
2004
Mutations in the Raf signaling pathway are known to play a pivotal role in the progression of malignant melanoma. In this study… (More)
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Highly Cited
2003
Highly Cited
2003
Protein kinase C (PKC) regulates activation of the Raf-1 signaling cascade by growth factors, but the mechanism by which this… (More)
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Highly Cited
2003
Highly Cited
2003
Feedback inhibition is a fundamental principle in signal transduction allowing rapid adaptation to different stimuli. In… (More)
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Highly Cited
2001
Highly Cited
2001
The Raf kinase inhibitor protein (RKIP) acts as a negative regulator of the mitogen-activated protein (MAP) kinase (MAPK) cascade… (More)
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Highly Cited
2000
Highly Cited
2000
We have recently identified the Raf kinase inhibitor protein (RKIP) as a physiological endogenous inhibitor of the Raf-1/MEK… (More)
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Highly Cited
1999
Highly Cited
1999
Raf-1 phosphorylates and activates MEK-1, a kinase that activates the extracellular signal regulated kinases (ERK). This kinase… (More)
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