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XAB2 gene

Known as: XPA binding protein 2, SYF1 homolog, RNA splicing factor (S. cerevisiae), SYF1 
National Institutes of Health

Related topics

Related topics

1 relation
PEBP1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Phase II study of nivolumab and salvage nivolumab + ipilimumab in treatment-naïve patients (pts) with advanced renal cell carcinoma (RCC) (HCRN GU16-260).
5006Background: Nivolumab (nivo) is FDA approved for pts with VEGFR TKI-resistant RCC and the nivo + ipilimumab (nivo/ipi… 
2019
2019
Randomized double-blind phase II study of maintenance pembrolizumab versus placebo after first-line chemotherapy in patients (pts) with metastatic urothelial cancer (mUC): HCRN GU14-182.
4504 Background: Platinum-based chemotherapy for 1st-line treatment of pts with metastatic urothelial cancer (mUC) is typically… 
2016
2016
Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination
We examined the influence of the tetratricopeptide repeat factor XAB2 on chromosomal break repair, and found that XAB2 promotes… 
2016
2016
XAB2 functions in mitotic cell cycle progression via transcriptional regulation of CENPE
Xeroderma pigmentosum group A (XPA)-binding protein 2 (XAB2) is a multi-functional protein that plays critical role in processes… 
2016
2016
HCRN GU14-188: Neoadjuvant pembrolizumab (P) and gemcitabine (G) with or without cisplatin (C) in muscle invasive urothelial cancer (MIUC).
TPS4578Background: Neoadjuvant chemotherapy (NAC) with C prior to cystectomy prolongs survival and increases the cure rate in… 
2009
2009
Ntc90 is required for recruiting first step factor Yju2 but not for spliceosome activation.
The Prp19-associated complex (NineTeen Complex [NTC]) is required for spliceosome activation by specifying interactions of U5 and… 
Highly Cited
2008
Highly Cited
2008
Isolation of XAB2 Complex Involved in Pre-mRNA Splicing, Transcription, and Transcription-coupled Repair*
Nucleotide excision repair is a versatile repair pathway that counteracts the deleterious effects of various DNA lesions. In… 
2007
2007
Knockdown of XAB2 enhances all-trans retinoic acid-induced cellular differentiation in all-trans retinoic acid-sensitive and -resistant cancer cells.
Xeroderma pigmentosum group A (XPA)-binding protein 2 (XAB2) is composed of 855 amino acids, contains 15 tetratricopeptide repeat… 
2005
2005
Disruption of mouse XAB2 gene involved in pre-mRNA splicing, transcription and transcription-coupled DNA repair results in preimplantation lethality.
2002
2002
Crooked neck is a component of the human spliceosome and implicated in the splicing process.
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