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PDGFRA wt Allele

Known as: PDGFR2, CD140A, Platelet-Derived Growth Factor Receptor, Alpha Polypeptide wt Allele 
Human PDGFRA wild-type allele is located within 4q11-q13 and is approximately 69 kb in length. This allele, which encodes alpha platelet-derived… 
National Institutes of Health

Related topics

Related topics

15 relations
4q11-q13Cell Migration PathwayCell ProliferationGastrointestinal Stromal Tumors

Broader (1)

PDGFRA gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
À propos d’un cas de tumeurs stromales gastriques chez l’enfant
RésuméLes tumeurs stromales gastro-intestinales (GIST) sont les tumeurs mésenchymateuses les plus fréquentes du tube digestif… 
2015
2015
Diagnosis value of CD117 and PDGFRA, alone or in combination DOG1, as biomarkers for gastrointestinal stromal tumors.
BACKGROUND To explore the diagnostic values of CD117 and PDGFRA protein expressions, used alone or in combination with DOG1… 
Review
2013
Review
2013
Hämatoonkologische Krankheitsbilder
ZusammenfassungDie Hemmkörperhämophilie ist eine lebensbedrohliche Erkrankung, die durch das Auftreten von Antikörpern gegen… 
2013
2013
Large-scale Analysis of PDGFRA Mutations in Melanomas and Evaluation of Their Sensitivity to Tyrosine Kinase Inhibitors Imatinib and Crenolanib
Purpose: Platelet-derived growth factor receptor α (PDGFRA) is a target for tyrosine kinase inhibitor (TKI)-based targeted… 
2012
2012
High KIT and PDGFRA are associated with shorter patients survival in gastroenteropancreatic neuroendocrine tumors, but mutations are a rare event
Purpose(1) To test whether in genomewide expression profiling differentially expressed genes were also distinct on the protein… 
2012
2012
Mutationsbasierter Therapiealgorithmus bei gastrointestinalen Stromatumoren
ZusammenfassungBei gastrointestinalen Stromatumoren finden sich in mindestens 85% der Fälle aktivierende Mutationen der… 
2010
2010
Novel therapy targets for DIPG
volume 7 | June 2010 | 298 research highlights at present, there are no effective therapy options for patients with diffuse… 
2006
2006
Loss of heterozygosity with acquisition of homozygous KIT-activating mutation promotes gastrointestinal stromal tumor progression.
9530 Background: Gastrointestinal stromal tumors (GISTs) originate from interstitial cells of Cajal and represent the most common… 
Highly Cited
1999
Highly Cited
1999
Close association between sequence polymorphism in the KIT gene and the roan coat color in horses
Abstract. The roan coat color in horses is controlled by a dominant allele that is lethal in the homozygous condition. Phenotypic… 
1991
1991
Chromosomal localization of the gene for AA-type platelet-derived growth factor receptor (PDGFRA) in humans and mice.
The full-length cDNA of the receptor for human AA-type platelet-derived growth factor (PDGF) was used to assign the PDGFRA gene… 
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