PDE2A wt Allele

Known as: Phosphodiesterase 2A, cGMP-Stimulated wt Allele, CGS-PDE, PDE2A1 
Human PDE2A wild-type allele is located in the vicinity of 11q13.4 and is approximately 98 kb in length. This allele, which encodes cGMP-dependent 3… Expand
National Institutes of Health

Papers overview

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2017
2017
OBJECTIVES To determine the ability of 11 sildenafil analogues to discriminate between cyclic nucleotide phosphodiesterases… Expand
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2016
2016
In Zoccarato et al. (Zoccarato et al. 2015), we provide extensive evidence that inhibition of PDE2 counteracts cardiac myocyte… Expand
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2013
2013
Phosphodiesterase 2 (PDE2) is an enzyme responsible for hydrolysis of cyclic adenosine monophosphate (cAMP) and cyclic guanosine… Expand
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2009
2009
The cGMP-stimulated PDE2A hydrolyzes both cyclic nucleotides, cGMP and cAMP. Three splice variants have been cloned from several… Expand
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2009
2009
Background The cyclic nucleotide second messengers cAMP and cGMP play key roles in mammalian signal transduction. Their… Expand
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1997
1997
Human cyclic GMP-stimulated 3',5'-cyclic nucleotide phosphodiesterase (PDE2A3) cDNAs were cloned from hippocampus and fetal brain… Expand
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