PDCD1 wt Allele

Known as: PD1, Systemic Lupus Erythematosus Susceptibility 2 Gene, CD279 
Human PDCD1 wild-type allele is located in the vicinity of 2q37.3 and is approximately 9 kb in length. This allele, which encodes programmed cell… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2017
01219972017

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2017
2017
The mAb pembrolizumab was purchased from Sino Biological by customer service. The Fab fragment was obtained by digestion of the… (More)
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2017
2017
Nivolumab is a monoclonal antibody directed against PD1 (programmed cell death 1) that can improve survival in patients with… (More)
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2015
2015
A mong the inter-related family of classical autoimmune diseases, primary biliary cirrhosis (PBC) is archetypal. It has one of… (More)
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Review
2014
Review
2014
Immunologic checkpoint inhibitor is a new class of antineoplastic drugs which mechanism of action depends on the interaction with… (More)
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2011
2011
OBJECTIVES Programmed cell death 1 (PDCD-1, also named PD-1, CD279, and SLEB2), a negative T cell regulator to maintain… (More)
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Review
2009
Review
2009
BACKGROUND Linkage studies suggest a locus, SLEB2, involved in susceptibility to systemic lupus erythematosus (SLE) and… (More)
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Highly Cited
2002
Highly Cited
2002
Systemic lupus erythematosus (SLE, OMIM 152700) is a complex autoimmune disease that affects 0.05% of the Western population… (More)
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Highly Cited
2000
Highly Cited
2000
To identify chromosomal regions containing susceptibility loci for systemic lupus erythematosus (SLE), we performed genome scans… (More)
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2000
2000
We have previously reported linkage of systemic lupus erythematosus to chromosome 2q37 in multicase families from Iceland and… (More)
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1997
1997
We report the complete cDNA sequence and the genomic structure of the human PD-1 homologue. An analysis of the expression pattern… (More)
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