PDCD1 gene

Known as: CD279 ANTIGEN, PD1, CD279 
This gene plays a role in apoptosis.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
BACKGROUND The immune checkpoint inhibitor ipilimumab is the standard-of-care treatment for patients with advanced melanoma… (More)
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Highly Cited
2014
Highly Cited
2014
PURPOSE Programmed cell death 1 (PD-1) is an inhibitory receptor expressed by activated T cells that downmodulates effector… (More)
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Highly Cited
2011
Highly Cited
2011
Chromosomal translocations are critically involved in the molecular pathogenesis of B-cell lymphomas, and highly recurrent and… (More)
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Highly Cited
2007
Highly Cited
2007
A small population of plasmacytoid DCs (pDCs) in mouse tumor-draining LNs can express the immunoregulatory enzyme indoleamine 2,3… (More)
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Highly Cited
2007
Highly Cited
2007
The ligands for programmed cell death 1 (PD-1), an immunoinhibitory receptor belonging to CD28/cytotoxic T lymphocyte antigen 4… (More)
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Review
2007
Review
2007
The programmed cell death 1 (PD-1) surface receptor binds to two ligands, PD-L1 and PD-L2. Studies have shown that PD-1–PD-L… (More)
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Highly Cited
2005
Highly Cited
2005
Mice deficient in programmed cell death 1 (PD-1, Pdcd1), an immunoinhibitory receptor belonging to the CD28/cytotoxic T… (More)
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Highly Cited
2005
Highly Cited
2005
OBJECTIVE The programmed death 1 (PD-1) molecule is a negative regulator of T cells, and a genetic association between PD-1 and… (More)
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Highly Cited
2002
Highly Cited
2002
Systemic lupus erythematosus (SLE, OMIM 152700) is a complex autoimmune disease that affects 0.05% of the Western population… (More)
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Highly Cited
1994
Highly Cited
1994
A cDNA encoding mouse PD-1, a member of the immunoglobulin superfamily was previously isolated from apoptosis-induced cells by… (More)
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