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PD168393

National Institutes of Health

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Quinazolines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
EGFR signaling augments TLR4 cell surface expression and function in macrophages via regulation of Rab5a activation
Toll-like receptor 4 (TLR4) is a key receptor sensing bacterial lipopolysaccharide (LPS), and is the most investigated member of… 
2013
2013
Long-lasting inhibition of EGFR autophosphorylation in A549 tumor cells by intracellular accumulation of non-covalent inhibitors.
2012
2012
A re-assessment of the effects of treatment with an epidermal growth factor receptor (EGFR) inhibitor on recovery of bladder and locomotor function following thoracic spinal cord injury in rats
2012
2012
The pan erbB inhibitor PD168393 enhances lysosomal dysfunction-induced apoptotic death in malignant peripheral nerve sheath tumor cells.
Malignant peripheral nerve sheath tumors (MPNSTs) are rapidly progressive Schwann cell neoplasms. The erbB family of membrane… 
2012
2012
Comments on the re-assessment study by Sharp et al. of Erschbamer et al.
2011
2011
Epidermal growth factor upregulates serotonin transporter in human intestinal epithelial cells via transcriptional mechanisms.
Serotonin transporter (SERT) regulates extracellular availability of serotonin and is a potential pharmacological target for… 
2011
2011
Phenylbutyrate suppresses distinct skin reactions that are enhanced by blockade of epidermal growth factor receptor signaling.
2007
2007
Amniotic fluid induces rapid epithelialization in the experimentally ruptured fetal mouse palate--implications for fetal wound healing.
Cleft of the secondary palate is one of the most common congenital birth defects in humans. The primary cause of cleft palate… 
Highly Cited
2005
Highly Cited
2005
Activation of the neuregulin-1/ErbB signaling pathway promotes the proliferation of neoplastic Schwann cells in human malignant peripheral nerve sheath tumors
Patients with neurofibromatosis type 1 develop aggressive Schwann cell neoplasms known as malignant peripheral nerve sheath… 
Review
2003
Review
2003
The epidermal growth factor receptor pathway and its inhibition as anticancer therapy.
Epidermal growth factor receptor (EGFR) is commonly overexpressed in a number of epithelial malignancies and is often associated… 
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