PCI 34051

Known as: PCI-34051, PCI34051 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2008-2018
02420082018

Papers overview

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2017
2017
Histone deacetylases (HDACs) are involved in epigenetic modulation and their aberrant expression has been demonstrated in… (More)
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2017
2017
Histone deacetylase 8 (HDAC8) is a promising drug target for multiple therapeutic applications. Here, we describe the modeling… (More)
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2016
2016
Epithelial-mesenchymal transition (EMT) and renal fibrosis are closely involved in chronic kidney disease. Inhibition of histone… (More)
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2016
2016
The histone deacetylase (HDAC) family regulates many biological pathways through the deacetylation of lysine residues on histone… (More)
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2016
2016
AIMS Alterations in histone proteins can lead to breast tumorigenesis. Selective histone deacetylase 8 (HDAC8) inhibitors with… (More)
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2016
2016
Many pathogenic microbes often release toxins that subvert the host's immune responses to render the environment suitable for… (More)
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2016
2016
To investigate the therapeutic effects of various HDAC inhibitors on the development of chronic allergic airway disease in mice… (More)
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2014
2014
Macrophages pre-exposed to a sublethal dose of anthrax lethal toxin (LeTx) are refractory to subsequent high cytolytic doses of… (More)
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2014
2014
Histone deacetylase (HDAC) inhibition improves function and extends survival in rodent models of a host of neurological… (More)
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Highly Cited
2008
Highly Cited
2008
We have developed a potent, histone deacetylase 8 (HDAC8)-specific inhibitor PCI-34051 with >200-fold selectivity over the other… (More)
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