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PCI 34051

Known as: PCI-34051, PCI34051 
 
National Institutes of Health

Papers overview

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2019
2019
ABSTRACT Triple‐negative breast cancer (TNBC) shows highly aggressive clinical behaviors and poor prognosis compared to other… Expand
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2019
2019
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is considered as a promising anti-cancer therapeutic. However… Expand
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2016
2016
The histone deacetylase (HDAC) family regulates many biological pathways through the deacetylation of lysine residues on histone… Expand
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2016
2016
Objective and designTo investigate the therapeutic effects of various HDAC inhibitors on the development of chronic allergic… Expand
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2016
2016
AIMS Alterations in histone proteins can lead to breast tumorigenesis. Selective histone deacetylase 8 (HDAC8) inhibitors with… Expand
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Review
2014
Review
2014
Human immunodeficiency virus type-1 (HIV-1) invades the central nervous system (CNS) during acute infection which can result in… Expand
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2014
2014
Macrophages pre-exposed to a sublethal dose of anthrax lethal toxin (LeTx) are refractory to subsequent high cytolytic doses of… Expand
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2012
2012
Histone deacetylases (HDACs) are a family of enzymes that play a crucial role in biological process and diseases. In contrast to… Expand
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Highly Cited
2008
Highly Cited
2008
We have developed a potent, histone deacetylase 8 (HDAC8)-specific inhibitor PCI-34051 with >200-fold selectivity over the other… Expand
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2008
2008
Inhibitors of histone deacetylases (HDACs) which are currently in clinical testing for treating various cancers typically inhibit… Expand
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