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PAX8 protein, human

Known as: paired box gene 8, human, paired domain gene 8, human, Pax-8 protein, human 
Paired box protein Pax-8 (450 aa, ~48 kDa) is encoded by the human PAX8 gene. This protein is involved in the differentiation of thyroid follicular… 
National Institutes of Health

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Related topics

14 relations
Cell NucleusDNA-Binding ProteinsGenes, RegulatorHistogenic Process

Broader (1)

PAX8 Transcription Factor

Papers overview

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2019
2019
Metastazující světlobuněčný renální karcinom bez zjevného primárního ložiska v ledvině, imitující pokročilé stádium plicní malignity
Východiska: Světlobuněcný renalni karcinom (ccRC) představuje 65 až 70% karcinomů ledvin s maximem výskytu v 6. a 7. deceniu věku… 
2018
2018
Metastatic breast cancer with GATA3, CK7 and ER positivity? A diagnostic pitfall
Introduction: Carcinoma of unknown primary can often be a challenge for clinicians and pathologists, and immunohistochemical… 
2017
2017
PAX 8 Expression in Non-Epithelial and Germ Cell Gynecological Tumors
PAX8 is a cell-lineage specific transcription factor. It exerts a vital role in the development of thyroid gland, kidneys, and… 
2016
2016
Expression of WT 1 and PAX 8 in the epithelial tumours of Malaysian women with ovarian cancer
Background: Ovarian cancer is particularly lethal due to late stage at presentation. The subtypes behave differently with respect… 
2011
2011
Pax8 detection in well-differentiated pancreatic endocrine tumors: how reliable is it?
To the Editor: One of the most challenging areas in pancreatic endocrine tumor (PET) biology is the identification of specific… 
2008
2008
Poly ( ADP-ribose ) polymerase 1 binds to Pax 8 and inhibits its transcriptional activity
Pax8 is a transcription factor that plays an important role in the regulation of genes that are exclusively expressed in… 
2008
2008
Molekulare Mechanismen der Schilddrüsentumorgenese
Thyroid nodules are the most frequent endocrine disorder and occur in approximately 30 % of the German population. Thyroid… 
2007
2007
TITLE : Emerging Roles for PAX 8 in Ovarian Cancer and Endosalpingeal Development
Objectives. Epithelial ovarian carcinomas develop from ovarian surface epithelia that undergo complex differentiation to form… 
2006
2006
Functional analysis of pax2/5/8 genes and their genetic interactions in zebrafish ear development
Functional Analysis of pax2/5/8 Genes and Their Genetic Interactions in Zebrafish Ear Development. (May 2006) Su Jin Kwak, B.S… 
2002
2002
85 Interactions of thyroid spcific transcription factor 2 (TTF2) with TTF1 and PAX8: TTF2 is able to stimulate the transcriptional activity of TTF1 and PAX8 on the promoter of the thyroglobulin gene.