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PAX8 protein, human

Known as: paired box gene 8, human, paired domain gene 8, human, Pax-8 protein, human 
Paired box protein Pax-8 (450 aa, ~48 kDa) is encoded by the human PAX8 gene. This protein is involved in the differentiation of thyroid follicular… 
National Institutes of Health

Related topics

Related topics

14 relations
Cell NucleusDNA-Binding ProteinsGenes, RegulatorHistogenic Process

Broader (1)

PAX8 Transcription Factor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Pax8 controls thyroid follicular polarity through cadherin-16
ABSTRACT Organization of epithelial cells during follicular lumen formation is crucial for thyroid morphogenesis and function of… 
2014
2014
PAX8 Expression in Uterine Adenocarcinomas and Mesonephric Proliferations
PAX8 is a useful immunohistochemical marker for the diagnosis of gynecologic tract malignancies. Several studies have described… 
Review
2013
Review
2013
The Immunohistochemical Expression of Islet 1 and PAX8 by Rectal Neuroendocrine Tumors Should Be Taken into Account in the Differential Diagnosis of Metastatic Neuroendocrine Tumors of Unknown…
Rectal neuroendocrine tumors (NETs) can be classified by histologic pattern and secretory products. Recently, rectal NETs have… 
Highly Cited
2011
Highly Cited
2011
Immunohistochemical assessment of Pax8 expression during pancreatic islet development and in human neuroendocrine tumors
The paired box transcription factor Pax8 is critical for development of the eye, thyroid gland as well as the urinary and… 
2011
2011
Diagnostic Use of PAX8, CAIX, TTF-1, and TGB in Metastatic Renal Cell Carcinoma of the Thyroid
Clear-cell renal cell carcinoma (ccRCC) may present with metastatic lesions in patients with a concurrent undiagnosed primary or… 
2011
2011
Identification of Novel Pax8 Targets in FRTL-5 Thyroid Cells by Gene Silencing and Expression Microarray Analysis
Background The differentiation program of thyroid follicular cells (TFCs), by far the most abundant cell population of the… 
2008
2008
Pax8 protein stability is controlled by sumoylation.
The transcription factor Pax8 is involved in the morphogenesis of the thyroid gland and in the maintenance of the differentiated… 
2006
2006
PAX8 expression in human bladder cancer.
PAX8 is a transcription factor with a role in ontogenesis of the urinary tract. The aim of the present investigation was to… 
2006
2006
PAX8-peroxisome proliferator-activated receptor gamma (PPARgamma) disrupts normal PAX8 or PPARgamma transcriptional function and stimulates follicular thyroid cell growth.
Follicular thyroid carcinomas are associated with a chromosomal translocation that fuses the thyroid-specific transcription… 
2001
2001
Opposite association of two PPARG variants with cancer: overrepresentation of H449H in endometrial carcinoma cases and underrepresentation of P12A in renal cell carcinoma cases
Abstract. Peroxisome proliferator activated receptor γ (PPARγ) is a nuclear hormone receptor that has been shown to regulate… 
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