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PAX4 gene

Known as: PAIRED DOMAIN GENE 4, PAIRED BOX GENE 4, MODY9 
National Institutes of Health

Related topics

Related topics

1 relation
MATURITY-ONSET DIABETES OF THE YOUNG, TYPE 9 (disorder)

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Successful induction of sclerostin in human-derived fibroblasts by 4 transcription factors and its regulation by parathyroid hormone, hypoxia, and prostaglandin E2.
2016
2016
In Vitro Differentiation of Pluripotent Stem Cells into Functional β Islets Under 2D and 3D Culture Conditions and In Vivo Preclinical Validation of 3D Islets.
Since the advent of pluripotent stem cells, (embryonic and induced pluripotent stem cells), applications of such pluripotent stem… 
Highly Cited
2014
Highly Cited
2014
Transcriptional control of PAX4-regulated miR-144/451 modulates metastasis by suppressing ADAMs expression
Paired box gene 4 (PAX4) is a transcriptional modulator located on chromosome 7q32, and its expression is dysregulated in a… 
2012
2012
Defective PAX4 R192H transcriptional repressor activities associated with maturity onset diabetes of the young and early onset-age of type 2 diabetes.
2009
2009
Developmental and daily expression of the Pax4 and Pax6 homeobox genes in the rat retina: localization of Pax4 in photoreceptor cells
Pax4 is a homeobox gene encoding Pax4, a transcription factor that is essential for embryonic development of the endocrine… 
2003
2003
Regulation of Pax4 Paired Homeodomain Gene by Neuron-restrictive Silencer Factor*
An elucidation of the key regulatory factors in pancreas development is critical for understanding the pathogenesis of diabetes… 
2003
2003
PAX4 mutation (R121W) as a prodiabetic variant in Okinawans.
2001
2001
Changes in the expression of transcription factors in pancreatic AR42J cells during differentiation into insulin-producing cells.
Pancreatic AR42J cells possess both exocrine and neuroendocrine properties and convert to insulin-producing cells upon treatment… 
Highly Cited
2000
Highly Cited
2000
Autoregulation and Maturity Onset Diabetes of the Young Transcription Factors Control the Human PAX4 Promoter*
During pancreatic development, the paired homeodomain transcription factor PAX4 is required for the differentiation of the… 
1999
1999
No evidence of linkage or diabetes-associated mutations in the transcription factors BETA2/NEUROD1 and PAX4 in Type II diabetes in France
Aims/hypothesis. The identification of mutations in hepatocyte nuclear factors-1α, –4α, –1β and insulin promoter factor-1 in… 
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