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PARP4 gene

Known as: VAULT POLY(ADP-RIBOSE) POLYMERASE, VAULT3, POLY(ADP-RIBOSE) POLYMERASE 4 
National Institutes of Health

Related topics

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Broader (1)

Genes

Papers overview

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2016
2016
Germline PARP4 mutations in patients with primary thyroid and breast cancers.
Germline mutations in the PTEN gene, which cause Cowden syndrome, are known to be one of the genetic factors for primary thyroid… 
2014
2014
Poly(ADP-ribose) Polymerase Inhibitors Sensitize Cancer Cells to Death Receptor-mediated Apoptosis by Enhancing Death Receptor Expression*
Background: Factors affecting death ligand sensitivity are incompletely understood. Results: PARP inhibitors increased CD95 and… 
Review
2007
Review
2007
PolyADP‐ribosylation and cancer
The polyADP‐ribosylation reaction results in a unique post‐translational modification involved in various cellular processes and… 
Review
2005
Review
2005
Poly(ADP-ribose)polymerase inhibition - where now?
The poly(ADP-ribose)polymerases (PARPs) catalyse the transfer of ADP-ribose units from the substrate NAD(+) to acceptor proteins… 
Highly Cited
2004
Highly Cited
2004
Expression of Mutant p193 and p53 Permits Cardiomyocyte Cell Cycle Reentry After Myocardial Infarction in Transgenic Mice
Previous studies have demonstrated that expression of p193 and p53 mutants with dominant-interfering activities renders embryonic… 
2003
2003
Poly(ADP-ribose) polymerase as a key player in excitotoxicity and post-ischemic brain damage.
Highly Cited
2002
Highly Cited
2002
Structural domains of vault proteins: a role for the coiled coil domain in vault assembly.
Vaults consist of multiple copies of three proteins (MVP, VPARP, and TEP1) and several untranslated RNAs. The function of vaults… 
Highly Cited
2001
Highly Cited
2001
Up‐regulation of vaults may be necessary but not sufficient for multidrug resistance
Vaults are ribonucleoprotein complexes comprised of the 100 kDa major vault protein (MVP), the 2 high m.w. vault proteins p193… 
2001
2001
Coexpression of Mutant p53 and p193 Renders Embryonic Stem Cell-Derived Cardiomyocytes Responsive to the Growth-Promoting Activities of Adenoviral E1A
Abstract— Expression of adenoviral E1A in cardiomyocytes results in the activation of DNA synthesis followed by apoptosis. In… 
Highly Cited
2000
Highly Cited
2000
Simian Virus 40 Large T Antigen Binds a Novel Bcl-2 Homology Domain 3-containing Proapoptosis Protein in the Cytoplasm*
A 193-kDa SV40 large T antigen (T-Ag)-binding protein, designated p193, was identified and cloned. Inspection of the deduced… 
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