Skip to search formSkip to main contentSkip to account menu

PARD6A gene

Known as: Partitioning Defective-6 Homolog Alpha, Par-6 Partitioning Defective 6 Homolog Alpha, par-6 family cell polarity regulator alpha 
Partitioning defective 6 homolog alpha (346 aa, ~37 kDa) is encoded by the human PARD6A gene. This protein is involved in tight junction formation… 
National Institutes of Health

Related topics

Related topics

10 relations
Adaptor Signaling Protein GeneAxon GuidanceCell ProliferationHomo sapiens

Narrower (1)

PARD6A wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Transgenic expression of constitutively active RAC1 disrupts mouse rod morphogenesis.
PURPOSE Dominant-active RAC1 rescues photoreceptor structure in Drosophila rhodopsin-null mutants, indicating an important role… 
Highly Cited
2012
Highly Cited
2012
Involvement of Girdin in the Determination of Cell Polarity during Cell Migration
Cell migration is a critical cellular process that determines embryonic development and the progression of human diseases… 
2012
2012
Formation of a PKCζ/β-catenin complex in endothelial cells promotes angiopoietin-1-induced collective directional migration and angiogenic sprouting.
Angiogenic sprouting requires that cell-cell contacts be maintained during migration of endothelial cells. Angiopoietin-1 (Ang-1… 
2009
2009
Seeing the trees despite the forest: applying recursive partitioning to the evaluation of drug treatment retention.
2008
2008
Regulation of epithelial and endothelial junctions by PAR proteins.
The organization of tissues depends on intercellular junctions that connect individual cells to each other. In sheets of… 
2006
2006
Expression of JAM-A, AF-6, PAR-3 and PAR-6 during the assembly and remodeling of RPE tight junctions
2006
2006
The development of 3D-QSAR study and recursive partitioning of heterocyclic quinone derivatives with antifungal activity.
Highly Cited
2005
Highly Cited
2005
Behavior of tight-junction, adherens-junction and cell polarity proteins during HNF-4alpha-induced epithelial polarization.
Highly Cited
2004
Highly Cited
2004
Isoforms of the Polarity Protein Par6 Have Distinct Functions*
PAR-6 is essential for asymmetric division of the Caenorhabditis elegans zygote. It is also critical for cell polarization in… 
2002
2002
Over‐expression of PAR‐3 suppresses contact‐mediated inhibition of cell migration in MDCK cells
Background: PAR‐3 is one of the PAR proteins, previously named ASIP, which are indispensable for the establishment of cell… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)