PARD6A gene

Known as: Partitioning Defective-6 Homolog Alpha, Par-6 Partitioning Defective 6 Homolog Alpha, par-6 family cell polarity regulator alpha 
Partitioning defective 6 homolog alpha (346 aa, ~37 kDa) is encoded by the human PARD6A gene. This protein is involved in tight junction formation… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Collective cell migration occurs in a range of contexts: cancer cells frequently invade in cohorts while retaining cell–cell… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Integral to the function and morphology of the epithelium is the lattice of cell-cell junctions known as adherens… (More)
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Highly Cited
2005
Highly Cited
2005
The transition of cells from an epithelial to a mesenchymal phenotype is a critical event during morphogenesis in multicellular… (More)
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Highly Cited
2005
Highly Cited
2005
The par (partitioning-defective) genes express a set of conserved proteins that function in polarization and asymmetric cell… (More)
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Highly Cited
2005
Highly Cited
2005
A polarity complex of PAR-3, PAR-6 and atypical protein kinase C (aPKC) functions in various cell-polarization events, including… (More)
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Highly Cited
2004
Highly Cited
2004
The C. elegans PAR proteins PAR-3, PAR-6, and PKC-3 are asymmetrically localized and have essential roles in cell polarity. We… (More)
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Highly Cited
2004
Highly Cited
2004
The establishment of a polarized morphology is an essential step in the differentiation of neurons with a single axon and… (More)
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Highly Cited
2003
Highly Cited
2003
Tight junctions help establish polarity in mammalian epithelia by forming a physical barrier that separates apical and… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Epithelial cells have apicobasal polarity and an asymmetric junctional complex that provides the bases for development… (More)
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Review
2001
Review
2001
Two PDZ-domain-containing adapter-like proteins, PAR-3 and PAR-6, and a protein kinase, atypical protein kinase C (PKC… (More)
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