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PAN 811

Known as: PAN-811, PAN811 
National Institutes of Health

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Broader (1)

3-aminopyridine-2-carboxaldehyde thiosemicarbazone

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
PAN-811 Blocks Chemotherapy Drug-Induced In Vitro Neurotoxicity, While Not Affecting Suppression of Cancer Cell Growth
Chemotherapy often results in cognitive impairment, and no neuroprotective drug is now available. This study aimed to understand… 
2010
2010
Gateways to clinical trials.
Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the… 
2010
2010
Gateways to clinical trials.
Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the… 
2009
2009
PAN-811 inhibits oxidative stress-induced cell death of human Alzheimer's disease-derived and age-matched olfactory neuroepithelial cells via suppression of intracellular reactive oxygen species.
Oxidative stress plays a significant role in neurotoxicity associated with a variety of neurodegenerative diseases including… 
2008
2008
Gateways to clinical trials. July-August 2008.
(-)-Epigallocatechin gallate, 501516, 89-12; Abatacept, Adalimumab, Adefovir dipivoxil, AG-701, Agatolimod sodium, Alefacept… 
2007
2007
PAN-811 provides neuroprotection against glutamate toxicity by suppressing activation of JNK and p38 MAPK
Review
2006
Review
2006
Neuroprotective activity of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (PAN-811), a cancer therapeutic agent.
3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) is a highly-hydrophobic small molecule that was originally developed… 
2006
2006
A multifunctional cytoprotective agent that reduces neurodegeneration after ischemia
Cellular and molecular pathways underlying ischemic neurotoxicity are multifaceted and complex. Although many potentially… 
2006
2006
Neurological diseases: Making steps in stroke therapy
2005
2005
PAN-811 (3-Aminopyridine-2-carboxaldehyde thiosemicarbazone), a novel neuroprotectant, elicits its function in primary neuronal cultures by up-regulating Bcl-2 expression
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