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3-aminopyridine-2-carboxaldehyde thiosemicarbazone

Known as: 3-AP, 3-Apct, 3AP 
A synthetic heterocyclic carboxaldehyde thiosemicarbazone with potential antineoplastic activity. Triapine inhibits the enzyme ribonucleotide… 
National Institutes of Health

Related topics

Related topics

5 relations

Narrower (3)

NSC 663249PAN 811Triapine

Broader (2)

PyridinesThiosemicarbazones

Papers overview

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2004
2004
Charge redistribution on electronic excitation. Dipole moments of cis- and trans-3-aminophenol in their S(0) and S(1) electronic states.
Rotationally resolved electronic spectroscopy in the gas phase, in the absence and presence of an applied electric field, has… 
2004
2004
A phase II trial of 3-Aminopyridine-2-Carboxaldehyde Thiosemicarbazone (3-AP) in patients with metastatic breast cancer
864 Background: 3-Aminopyridine-2-Carboxaldehyde Thiosemicarbazone (3-AP, Triapine), a potent inhibitor of ribonucleotide… 
1999
1999
Effects of nicotinamide-related agents on the growth of primary rat hepatocytes and formation of small hepatocyte colonies.
AIMS/BACKGROUND We report in this study that, 10 mM nicotinamide can stimulate the proliferation of primary rat hepatocytes in… 
1994
1994
Transitory disappearance of microglia during the regeneration of the lizard medial cortex
In normal lizards, microglial cells populate the medial cortex (a zone homologous to the hippocampal fascia dentata), with a… 
1993
1993
Effect of nitrogen limitation on the biodegradability and toxicity of nitro- and aminophenol isomers to methanogenesis
Monosubstituted nitro- and aminophenol isomers exhibited limited biodegradability under methanogenic conditions when supplied as… 
1981
1981
Properties of tetraethylammonium ion-resistant K+ channels in the photoreceptor membrane of the giant barnacle
After the offset of illumination, barnacle photoreceptors undergo a large hyperpolarization that lasts seconds or minutes. We… 
1979
1979
Calcium channels in the high resistivity axonal membrane of photoreceptors of the giant barnacle.
1. The distribution of calcium channels in the cell membrane of the photoreceptor neurone of the giant barnacle, Balanus nubilus… 
1972
1972
The effects of the nicotinamide sensitive teratogen 3-acetylpyridine on chick limb mesodermal cells in culture: biochemical parameters.
  • A. Caplan
  • The Journal of experimental zoology
  • 1972
  • Corpus ID: 36126572
3-acetylpyridine (3AP) causes severe muscular hypoplasia in vivo and seems to potentiate chondrogenic expression of limb bud… 
1971
1971
The teratogenic action of the nicotinamide analgos 3-acetylpyridine and 6-aminonicotinamide on developing chick embryos.
  • A. Caplan
  • The Journal of experimental zoology
  • 1971
  • Corpus ID: 19129914
The nicotinamide analogs 3-acetylpyridine (3AP) and 6-amino-nicotinamide (6AN) have been reported to produce muscle and bone… 
1968
1968
Morphologische Befunde am Zentralnervensystem der Ratte nach Vergiftung mit Antimetaboliten des Nicotinamids (6-Aminonicotinsäureamid und 3-Acetylpyridin) und einem Chinolinderivat (5-Nitro-8…
Summary3-AcetyIpyridine caused irreversible motor disorders (waltzing and hyperkinesia). It was found that 6 months following a… 
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