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PAK 104P

Known as: PAK-104P, PAK104P 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Cyclic P-OxidesNicotinic Acids

Papers overview

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2002
2002
MRP1 modulation by PAK-104P: detection with technetium-99m-MIBI in cultured lung tumor cells.
BACKGROUND Resistance mediated by the MultiDrug Resistance protein (P-glycoprotein and MRP1), results in energy-dependent efflux… 
Review
1999
Review
1999
[Mechanisms for resistance to anticancer agents and the reversal of the resistance].
MDR results from overexpression of P-glycoprotein (Pgp) and multidrug resistance protein (MRP or MRP1) that function as ATP… 
1998
1998
Reversal of MRP-mediated vincristine resistance in KB cells by buthionine sulfoximine in combination with PAK-104P.
1996
1996
PAK-104P, a pyridine analogue, reverses paclitaxel and doxorubicin resistance in cell lines and nude mice bearing xenografts that overexpress the multidrug resistance protein.
Multidrug resistance (MDR) is considered multifactorial and has been associated with overexpression of the multidrug resistance… 
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