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PAK 104P

Known as: PAK-104P, PAK104P 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Cyclic P-OxidesNicotinic Acids

Papers overview

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2002
2002
MRP1 modulation by PAK-104P: detection with technetium-99m-MIBI in cultured lung tumor cells.
BACKGROUND Resistance mediated by the MultiDrug Resistance protein (P-glycoprotein and MRP1), results in energy-dependent efflux… 
2000
2000
Reversal of P-Glycoprotein and Multidrug-Resistance Protein-Mediated Drug Resistance in KB Cells by 5O-Benzoylated
A newly synthesized taxoid originally from the Japanese yew Taxus cuspidata, 5-O-benzoylated taxinine K (BTK) was examined for… 
Review
1999
Review
1999
[Mechanisms for resistance to anticancer agents and the reversal of the resistance].
MDR results from overexpression of P-glycoprotein (Pgp) and multidrug resistance protein (MRP or MRP1) that function as ATP… 
1998
1998
Reversal of MRP-mediated vincristine resistance in KB cells by buthionine sulfoximine in combination with PAK-104P.
Highly Cited
1997
Highly Cited
1997
Reversal of multidrug resistance-associated protein-mediated drug resistance by the pyridine analog PAK-104P.
Three agents, verapamil, cepharanthine, and 2-[4-(diphenylmethyl)-1-piperazinyl]ethyl-5-(trans-4,6-dimethyl-1, 3,2… 
1996
1996
PAK-104P, a pyridine analogue, reverses paclitaxel and doxorubicin resistance in cell lines and nude mice bearing xenografts that overexpress the multidrug resistance protein.
Multidrug resistance (MDR) is considered multifactorial and has been associated with overexpression of the multidrug resistance… 
Highly Cited
1990
Highly Cited
1990
Two pyridine analogues with more effective ability to reverse multidrug resistance and with lower calcium channel blocking activity than their dihydropyridine counterparts.
Four pyridine analogues and their dihydropyridine counterparts were examined for their ability to reverse drug resistance in a… 
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