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PAI 039

Known as: PAI-039, PAI039 cpd 
 
National Institutes of Health

Papers overview

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2013
2013
Background Systemic elevations in PAI-1 suppress the fibrinolytic pathway leading to poor collagen remodelling and delayed… Expand
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2012
2012
BACKGROUND Plasminogen activator inhibitor-1 (PAI-1) is a protease inhibitor but is paradoxically associated with poor outcomes… Expand
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2008
2008
OBJECTIVE To assess the antithrombotic and profibrinolytic effects of tiplaxtinin (PAI-039), an orally bioavailable antagonist of… Expand
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2008
2008
This study aimed to evaluate a small-molecule PAI-1 inhibitor (PAI-039; tiplaxtinin) in a rodent stenosis model of venous… Expand
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Highly Cited
2007
Highly Cited
2007
The inactivation of plasminogen activator inhibitor-1 (PAI-1) by the small molecule PAI-1 inhibitor PAI-039 (tiplaxtinin) has… Expand
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE The effect of a novel small molecule plasminogen activator inhibitor (PAI-1) inhibitor on adipose tissue physiology was… Expand
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2006
2006
BACKGROUND Plasminogen activator inhibitor-1 (PAI-1) is integrally involved in tumorigenesis by impacting on both proteolytic… Expand
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Highly Cited
2005
Highly Cited
2005
OBJECTIVE To test the hypothesis that pharmacological plasminogen activator inhibitor (PAI)-1 inhibition protects against renin… Expand
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2005
2005
We tested a novel, orally active inhibitor of plasminogen activator inhibitor-1 (PAI-1) in a canine model of electrolytic injury… Expand
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2005
2005
OBJECTIVES To investigate the role of plasminogen activator inhibitor-1 (PAI-1) in adipose tissue development and insulin… Expand
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