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PAI 039

Known as: PAI-039, PAI039 cpd 
National Institutes of Health

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Broader (1)

tiplaxtinin

Papers overview

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2018
2018
Evaluation of PAI-1 in endometriosis using a homologous immunocompetent mouse model†
Abstract To analyze the role of PAI-1 (plasminogen activator inhibitor 1) in endometriotic lesion growth, we studied the effect… 
2015
2015
Bevacizumab promotes venous thromboembolism through the induction of PAI-1 in a mouse xenograft model of human lung carcinoma
An increased incidence of venous thromboembolism (VTE) is associated with anti-vascular endothelial growth factor (VEGF… 
2014
2014
Cell Cycle and Senescence PAI-1 Leads to G 1-Phase Cell-Cycle Progression through Cyclin D 3 / cdk 4 / 6 Upregulation
The canonical function of plasminogen activator inhibitor-1 (PAI-1/SERPINE1) is as an inhibitor of urokinasetype plasminogen… 
2013
2013
Small Molecule Therapeutics Targeting Plasminogen Activator Inhibitor-1 Inhibits Angiogenesis and Tumor Growth in a Human Cancer Xenograft Model
Cancers of the urinary bladder result in aggressive and highly angiogenic tumors for which standard treatments have only limited… 
2012
2012
Inactivation of Plasminogen Activator Inhibitor-1 by RNA Aptamer Molecules
Abstract 1107 Introduction: The serine protease inhibitor (serpin) plasminogen activator inhibitor-1 (PAI-1), binds and inhibits… 
2012
2012
PAI-039, An Inhibitor Of Plasminogen Activator Inhibitor-1, Ameliorates Lung Injury Induced By Bleomycin
2011
2011
A Specific PAI-1 Inhibitor, PAI-039, Reduced Airway Inflammation And Collagen Deposition In An Ova-challenged Murine Model Of Chronic Asthma
2006
2006
Results Effect of PAI-039 on PAI-1 Secretion by Preadipocytes : Basal
Copyright © 2006 American Heart Association. All rights reserved. Print ISSN: 1079-5642. Online 7272 Greenville Avenue, Dallas… 
2005
2005
Evaluation of PAI-039 [{1-Benzyl-5-[4-(trifluoromethoxy)phenyl]-1H-indol-3-yl}(oxo)acetic Acid], a Novel Plasminogen Activator Inhibitor-1 Inhibitor, in a Canine Model of Coronary Artery Thrombosis
We tested a novel, orally active inhibitor of plasminogen activator inhibitor-1 (PAI-1) in a canine model of electrolytic injury… 
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