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PAI 039

Known as: PAI-039, PAI039 cpd 
 
National Institutes of Health

Papers overview

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2012
2012
Spatial and temporal regulation of the pericellular proteolytic environment by local growth factors, such as EGF and TGF… Expand
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Highly Cited
2012
Highly Cited
2012
BACKGROUND Plasminogen activator inhibitor-1 (PAI-1) is a protease inhibitor but is paradoxically associated with poor outcomes… Expand
Highly Cited
2011
Highly Cited
2011
OBJECTIVE Type 1 diabetes leads to impairments in growth, function, and regenerative capacity of skeletal muscle; however, the… Expand
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2008
2008
Summary.  Objective: To assess the antithrombotic and profibrinolytic effects of tiplaxtinin (PAI‐039), an orally bioavailable… Expand
2008
2008
This study aimed to evaluate a small-molecule PAI-1 inhibitor (PAI-039; tiplaxtinin) in a rodent stenosis model of venous… Expand
Highly Cited
2006
Highly Cited
2006
Objective—The effect of a novel small molecule plasminogen activator inhibitor (PAI-1) inhibitor on adipose tissue physiology was… Expand
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Highly Cited
2006
Highly Cited
2006
Summary.  Background: Plasminogen activator inhibitor‐1 (PAI‐1) is integrally involved in tumorigenesis by impacting on both… Expand
2005
2005
We tested a novel, orally active inhibitor of plasminogen activator inhibitor-1 (PAI-1) in a canine model of electrolytic injury… Expand
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Highly Cited
2005
Highly Cited
2005
Objective— To test the hypothesis that pharmacological plasminogen activator inhibitor (PAI)-1 inhibition protects against renin… Expand
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Highly Cited
2005
Highly Cited
2005
Summary.  Objectives: To investigate the role of plasminogen activator inhibitor‐1 (PAI‐1) in adipose tissue development and… Expand