PAI 039

Known as: PAI-039, PAI039 cpd 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2005-2017
012320052017

Papers overview

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2015
2015
Diabetes impairs the ability to heal cutaneous wounds, leading to hospitalization, amputations, and death. Patients with diabetes… (More)
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2013
2013
BACKGROUND Systemic elevations in PAI-1 suppress the fibrinolytic pathway leading to poor collagen remodelling and delayed… (More)
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2012
2012
BACKGROUND Plasminogen activator inhibitor-1 (PAI-1) is a protease inhibitor but is paradoxically associated with poor outcomes… (More)
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2008
2008
OBJECTIVE To assess the antithrombotic and profibrinolytic effects of tiplaxtinin (PAI-039), an orally bioavailable antagonist of… (More)
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2008
2008
This study aimed to evaluate a small-molecule PAI-1 inhibitor (PAI-039; tiplaxtinin) in a rodent stenosis model of venous… (More)
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2007
2007
The inactivation of plasminogen activator inhibitor-1 (PAI-1) by the small molecule PAI-1 inhibitor PAI-039 (tiplaxtinin) has… (More)
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2006
2006
OBJECTIVE The effect of a novel small molecule plasminogen activator inhibitor (PAI-1) inhibitor on adipose tissue physiology was… (More)
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2006
2006
BACKGROUND Plasminogen activator inhibitor-1 (PAI-1) is integrally involved in tumorigenesis by impacting on both proteolytic… (More)
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2005
2005
We tested a novel, orally active inhibitor of plasminogen activator inhibitor-1 (PAI-1) in a canine model of electrolytic injury… (More)
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2005
2005
OBJECTIVE To test the hypothesis that pharmacological plasminogen activator inhibitor (PAI)-1 inhibition protects against renin… (More)
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