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P2RX5 gene

Known as: P2X5, P2RX5, LRH-1 
National Institutes of Health

Related topics

Related topics

2 relations
P2RX6 geneReceptors, Purinergic P2X5

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
GATA6 enhances the stemness of human colon cancer cells by creating a metabolic symbiosis through upregulating LRH‐1 expression
Cancer stem cells play critical roles in tumor initiation, progression, and relapse. Since we previously found that GATA6… 
2019
2019
Altered allostery of the left flipper domain underlies the weak ATP response of rat P2X5 receptors
Although the extracellular ATP-gated cation channel purinergic receptor P2X5 is widely expressed in heart, skeletal muscle, and… 
2018
2018
The purinergic receptor P2X5 contributes to bone loss in experimental periodontitis
Purinergic receptor signaling is increasingly recognized as an important regulator of inflammation. The P2X family purinergic… 
Highly Cited
2015
Highly Cited
2015
Direct Evidence of Brown Adipocytes in Different Fat Depots in Children
Recent studies suggested the persistence of brown adipocytes in adult humans, as opposed to being exclusively present in infancy… 
Highly Cited
2009
Highly Cited
2009
Myeloid leukemic progenitor cells can be specifically targeted by minor histocompatibility antigen LRH-1-reactive cytotoxic T cells.
CD8(+) T cells recognizing minor histocompatibility antigens (MiHAs) on leukemic stem and progenitor cells play a pivotal role in… 
Highly Cited
2005
Highly Cited
2005
Coactivation of liver receptor homologue-1 by peroxisome proliferator-activated receptor gamma coactivator-1alpha on aromatase promoter II and its inhibition by activated retinoid X receptor suggest…
Aromatase inhibitors target the production of estrogen in breast adipose tissue, but in doing so, also decrease estrogen… 
Highly Cited
2005
Highly Cited
2005
P2X and P2Y purinergic receptors on human intestinal epithelial carcinoma cells: effects of extracellular nucleotides on apoptosis and cell proliferation.
Extracellular nucleotides interact with purinergic receptors, which regulate ion transport in a variety of epithelia. With the… 
Highly Cited
2001
Highly Cited
2001
A quantitative analysis of purinoceptor expression in human fetal and adult bladders.
Highly Cited
1999
Highly Cited
1999
Localisation of P2X5 and P2X7 receptors by immunohistochemistry in rat stratified squamous epithelia
Abstract In order to investigate whether purinoceptors are involved in the physiological renewal and regeneration of epithelia… 
Highly Cited
1996
Highly Cited
1996
Cloning OF P2X5 and P2X6 receptors and the distribution and properties of an extended family of ATP-gated ion channels
Two new P2X receptor cDNAs (P2X5 and P2X6) were isolated and expressed. All six proteins are 36–48 percent identical and seem to… 
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