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Oxytrex

 
National Institutes of Health

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Review
2009
Review
2009
Ultra-low-dose opioid antagonist cotreatment was first shown parad oxically to enhance opioid analgesia and to reduce analgesic… Expand
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Highly Cited
2008
Highly Cited
2008
UNLABELLED Both peripheral nerve injury and chronic opioid treatment can result in hyperalgesia associated with enhanced… Expand
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Review
2007
Review
2007
  • L. Webster
  • Expert opinion on investigational drugs
  • 2007
  • Corpus ID: 7133998
Oxytrex® (Pain Therapeutics, Inc.) is an oral opioid that combines a therapeutic amount of oxycodone with an ultra-low dose of… Expand
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2007
2007
B E T H E S D A , M D. — P hysicians can help minimize the potential for abuse of opioid pain medications by considering the… Expand
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Highly Cited
2006
Highly Cited
2006
UNLABELLED Physical dependence or withdrawal is an expected effect of prolonged opioid therapy. Oxytrex (oxycodone + ultralow… Expand
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2006
2006
Physical dependence or withdrawal is an expected effect of prolonged opioid therapy. Oxytrex (oxycodone ultralow-dose naltrexone… Expand
  • table 2
  • figure 1
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Highly Cited
2005
Highly Cited
2005
UNLABELLED Oxytrex is a novel drug that combines oxycodone with ultralow-dose naltrexone, an opioid antagonist. Ultralow-dose… Expand
  • figure 1
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2005
2005
Ultra-low-dose opioid antagonists, when combined with opiates, increase the analgesic efficacy and duration of analgesia of the… Expand
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2005
2005
  • W. Wolfson
  • Chemistry & biology
  • 2005
  • Corpus ID: 33895156
“We call opiates a double-edged sword or Janus faced,” says Angst. “They do a lot of good and potentially a lot of harm as well… Expand
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