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Ultra-low-dose opioid antagonist cotreatment was first shown parad oxically to enhance opioid analgesia and to reduce analgesic… Expand UNLABELLED
Both peripheral nerve injury and chronic opioid treatment can result in hyperalgesia associated with enhanced… Expand Oxytrex® (Pain Therapeutics, Inc.) is an oral opioid that combines a therapeutic amount of oxycodone with an ultra-low dose of… Expand B E T H E S D A , M D. — P hysicians can help minimize the potential for abuse of opioid pain medications by considering the… Expand UNLABELLED
Physical dependence or withdrawal is an expected effect of prolonged opioid therapy. Oxytrex (oxycodone + ultralow… Expand Physical dependence or withdrawal is an expected effect of prolonged opioid therapy. Oxytrex (oxycodone ultralow-dose naltrexone… Expand UNLABELLED
Oxytrex is a novel drug that combines oxycodone with ultralow-dose naltrexone, an opioid antagonist. Ultralow-dose… Expand Ultra-low-dose opioid antagonists, when combined with opiates, increase the analgesic efficacy and duration of analgesia of the… Expand “We call opiates a double-edged sword or Janus faced,” says Angst. “They do a lot of good and potentially a lot of harm as well… Expand