Oxycodone

Known as: Oxycodone SR, Oxycodeinon, Dihydrone 
A semi-synthetic, morphine-like opioid alkaloid with analgesic activity. Oxycodone exerts its analgesic activity by binding to the mu-receptors in… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1950-2019
010020019502018

Papers overview

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Highly Cited
2010
Highly Cited
2010
BACKGROUND Tapentadol is a novel, centrally acting analgesic with mu-opioid receptor agonist and norepinephrine reuptake… (More)
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Highly Cited
2008
Highly Cited
2008
SUMMARY OF CONSENSUS: 1. The use of opioids in cancer pain: The criteria for selecting analgesics for pain treatment in the… (More)
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Highly Cited
2008
Highly Cited
2008
OBJECTIVE Opioid therapy is frequently associated with treatment-limiting constipation. Naloxone is an opioid antagonist with low… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND In vitro experiments suggest that circulating metabolites of oxycodone are opioid receptor agonists. Clinical and… (More)
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Highly Cited
2004
Highly Cited
2004
Oxycodone undergoes N-demethylation to noroxycodone and O-demethylation to oxymorphone. The cytochrome P450 (P450) isoforms… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Painful neuropathy is one of the most common long-term complications of diabetes mellitus and often proves difficult… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND AND OBJECTIVE Opioid treatment has played a limited role in the management of diabetic neuropathy, in part because of… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Although opioid analgesics have well-defined efficacy and safety in treatment of chronic cancer pain, further research… (More)
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Highly Cited
1998
Highly Cited
1998
OBJECTIVE Although opioid analgesics are used in the management of neuropathic pain syndromes, evidence of their efficacy remains… (More)
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Highly Cited
1992
Highly Cited
1992
1. The pharmacokinetics and metabolism of oxycodone were studied in nine healthy young volunteers in a cross-over study. Each… (More)
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