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Ibogaine in the treatment of heroin withdrawal.
Quantitation of N,N-dimethyltryptamine and harmala alkaloids in human plasma after oral dosing with ayahuasca.
Harmine, harmaline, tetrahydroharmine (THH), and N,N-dimethyltryptamine (DMT) were quantitated in plasma from 15 healthy male volunteers after the ingestion of ayahuasca, a beverage that has beenExpand
Medication development of ibogaine as a pharmacotherapy for drug dependence.
The potential for deriving new psychotherapeutic medications from natural sources has led to renewal interest in rain forest plants as a source of lead compounds for the development of antiaddictionExpand
Brain biomarkers for identifying excited delirium as a cause of sudden death.
Excited delirium (ED) syndrome is a serious medical condition associated with acute onset of agitated violent behavior that often culminates in a sudden unexplained death. While the contribution ofExpand
Cocaethylene: A Unique Cocaine Metabolite Displays High Affinity for the Dopamine Transporter
Abstract: Concurrent cocaine and alcohol use is common practice in the general population, as indicated by recent prevalence studies. In the presence of ethyl alcohol, cocaine is metabolized to itsExpand
Site-dependent postmortem changes in blood cocaine concentrations.
When a forensic toxicologist interprets postmortem blood cocaine findings he usually must make assumptions regarding perimortem drug concentrations. In-vitro studies have shown that cocaine rapidlyExpand
Chapter 8 Ibogaine in the treatment of heroin withdrawal
Publisher Summary The chapter presents a study on the role of ibogaine in the treatment of heroin withdrawal. Pharmacological treatments for heroin addiction currently employ two treatmentExpand
High affinity cocaine recognition sites on the dopamine transporter are elevated in fatal cocaine overdose victims.
Cocaine mediates its powerful reinforcement by binding to recognition sites on the dopamine (DA) transporter. The pharmacological identity of cocaine recognition sites and their relevance to dopamineExpand
Recommendations for toxicological investigations of drug-facilitated sexual assaults.
The recent increase in reports of drug-facilitated sexual assaults has caused alarm in the general public and prompted forensic toxicologists from across North America to address the toxicologicalExpand
Medication Development of Ibogaine as a Pharmacotherapy for Drug Dependence a
ABSTRACT: The potential for deriving new psychotherapeutic medications from natural sources has led to renewed interest in rain forest plants as a source of lead compounds for the development ofExpand
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