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Oxyphenonium

Known as: Metacin, Oxyphenonium ion, 2-((Cyclohexylhydroxyphenylacetyl)oxy)-N,N-diethyl-N-methylethanaminium 
A quaternary ammonium anticholinergic agent with peripheral side effects similar to those of ATROPINE. It is used as an adjunct in the treatment of… 
National Institutes of Health

Related topics

Related topics

14 relations

Broader (5)

BenzilatesCholineMuscarinic AntagonistsMydriatics
In BloodPoisoning by parasympatholytics (anticholinergics and antimuscarinics) and spasmolyticsagonistsanalogs & derivatives

Narrower (1)

Oxyphenonium Bromide

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2001
2001
Effects of COX-1 and COX-2 inhibitors on eicosanoid biosynthesis and the release of substance P from the guinea-pig isolated perfused lung
Abstract:Objective: In the guinea-pig isolated perfused lung, co-administration of bradykinin (BK) and histamine causes the… 
1994
1994
Cerebral Blood Flow Responses to Indomethacin in Awake Newborn Pigs
ABSTRACT: The prostaglandin H-synthase inhibitor in-domethacin decreases cerebral blood flow (CBF) in newborn pigs. The duration… 
1985
1985
The effects of eicosanoid synthesis inhibitors on normoxic and hypoxic pulmonary vascular tone in dogs.
Prostaglandins have been implicated as possible modulators of normoxic and hypoxic pulmonary tone partly because of studies using… 
1984
1984
Prostaglandins and the regulation of motility in non-pregnant isolated uterus
1984
1984
Development of a sensitive radioreceptor assay for oxyphenonium in plasma and urine
A radioreceptor assay (RRA) for oxyphenonium has been developed. It is based on competition between [3H]dexetimide and… 
Highly Cited
1983
Highly Cited
1983
Influence of dietary fat and indomethacin on the growth of transplantable mammary tumors in rats.
Studies were designed to determine if treatment with indomethacin influenced the growth of a transplantable, metastatic, rat… 
1982
1982
Immune modulation of connective tissue functions: studies on the production of collagen synthesis inhibitory factor by populations of human peripheral blood mononuclear cells.
Highly Cited
1976
Highly Cited
1976
Effect of anti-inflammatory drugs on lysosomes and lysosomal enzymes from rat liver.
Highly Cited
1975
Highly Cited
1975
Hormonal and related factors affecting the release of prostaglandin F2alpha from the uterus.
1974
1974
Indomethacin potentiates PGE1 stimulated cyclic AMP accumulation in human synoviocytes
PROSTAGLANDINS have both inhibitory and stimulatory effects on inflammatory and immune processes1. The capacity of the… 
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