Oxyfedrine

Known as: Oxifedrine, 1-Propanone, 3-((2-hydroxy-1-methyl-2-phenylethyl)amino)-1-(3-methoxyphenyl)-, (R-(R*,S*))-, Oxiphedrin 
A drug used in the treatment of angina pectoris, heart failure, conduction defects, and myocardial infarction. It is a partial agonist at beta… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1968-2017
051019682017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
The cardiovascular drug oxyfedrine HCl revealed noteworthy in vitro antibacterial action against 501 strains of Gram positive and… (More)
Is this relevant?
2003
2003
Ten cardiovascular drugs, having diverse pharmacological action, were screened for possible antimicrobial property against known… (More)
Is this relevant?
1997
1997
Effect of oxyfedrine (OXF)(1 mg/kg) administered just before reperfusion (post-treatment) was investigated in a canine model of… (More)
Is this relevant?
1980
1980
1 In a group of 23 patients with documented ischaemic heart disease who experienced angina pectoris, oral oxyfedrine (24 mg three… (More)
Is this relevant?
1979
1979
1. Oxyfedrine, at concentrations of 10−7 to 3×10−6 mol/l, increased the force of contraction of the isolated papillary muscle of… (More)
  • figure 2
  • figure 3
  • figure 4
  • figure 6
  • figure 5
Is this relevant?
1974
1974
1 Haemodynamic changes have been studied in cats after the chronic oral administration of oxyfedrine (14 mg/kg for 3-4 weeks) or… (More)
Is this relevant?
1973
1973
Experiments in isolated, perfused guinea-pig hearts (Langendorff) have shown that 1. Inotropic effects of catecholamines and… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
1973
1973
It was the aim of the investigation to elucidate the mechanism of the sympathomimetic action of oxyfedrine [(-)-3-methoxy-ω-(1… (More)
  • table 1
  • figure 7
  • figure 8
  • figure 9
Is this relevant?
1972
1972
Pharmacokinetic studies with orally administered 14C-oxyfedrine were carried out in rats and also in men. 1. In the rat tissue… (More)
  • table 1
  • figure 1
  • figure 3
  • figure 6
  • figure 7
Is this relevant?
1971
1971
Oxyfedrine has cardiostimulant effects due to direct activation of beta-receptors. It is devoid of stimulant effects on beta… (More)
  • figure 1
Is this relevant?