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Osteonectin

Known as: Basement-Membrane Protein 40, SPARC Glycoprotein, Osteonectin [Chemical/Ingredient] 
Non-collagenous, calcium-binding glycoprotein of developing bone. It links collagen to mineral in the bone matrix. In the synonym SPARC glycoprotein… 
National Institutes of Health

Related topics

Related topics

22 relations
Bone remodelingCalcium BindingCell Cycle ControlExtracellular Matrix

Broader (2)

Extracellular Matrix ProteinsGlycoproteins

Narrower (3)

SMOC-1 protein, mouseSMOC-1 protein, ratSMOC1 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Ductal carcinoma in situ on stereotactic biopsy of suspicious breast microcalcifications: Expression of SPARC (Secreted Protein, Acidic and Rich in Cysteine) can predict postoperative invasion
Secreted protein, acidic and rich in cysteine (SPARC) is able to play an important role in cancer invasion due to de‐adhesive… 
2014
2014
Adiponectin effects on osteonectin gene expression in vascular smooth muscle cell line
Background and purpose: Atherosclerosis is a major cause of death in adults in most countries. Many studies have focused on the… 
Review
2012
Review
2012
Service Request on a critical review of the environmental and physicochemical methodologies commonly employed in the environmental risk assessment of petroleum substances in the context of REACH…
Review
2010
Review
2010
COMPACT BONE STRUCTURE OF UNMODIFIED AND GENETICALLY MODIFIED RABBITS
Bone, a relatively dense material in the sense of matrix, represents the main calcified tissue of the skeleton in mammals. Charac… 
2010
2010
SPARC microenvironment signature (SMS) in patients treated with nab-paclitaxel (nabP)/carboplatin (C)/bevacizumab(B) for triple-negative metastatic breast cancer (TNMBC).
e21040 Background: SPARC is an albumin-binding protein associated with poor prognosis that may mediate intratumoral accumulation… 
2010
2010
Use of SPARC, EGFR, and VEGFR expression to predict response to nab-paclitaxel (nabP)/carboplatin (C)/bevacizumab (B) chemotherapy in triple-negative metastatic breast cancer (TNMBC).
1109 Background: Improved therapies and predictive markers are needed in TNBC. B (bevacizumab) and C combinations are active in… 
2008
2008
SPARC and CA19–9 as biomarkers in patients with advanced pancreatic cancer treated with nab paclitaxel plus gemcitabine
15592 Background: Pancreatic cancers are known to overexpress SPARC (Secreted Protein And Rich in Cysteine) (Von Hoff et al… 
2003
2003
[Clinical application of tissue engineered bone repair of human craniomaxillofacial bone defects].
OBJECTIVE To explore the feasibility of tissue engineered bone formation in human being using human bone marrow stromal cells… 
2001
2001
Repair of annular disc lesions: Spatial and temporal localisation of TGF-beta, SPARC (Osteonectin, BM-40) and FGF-2 are early responses in experimentally injured ovine discs
+*Melrose, J (A-NHMRC); *Smith, S (A-NHMRC); **Little, C (A-The University of Wales); *Kitson, J (E-The Royal North Shore… 
1998
1998
Basic fibroblast growth factor destabilizes osteonectin mRNA in osteoblasts
Delany, Anne M., and Ernesto Canalis. Basic fibroblast growth factor destabilizes osteonectin mRNA in osteoblasts. Am. J. Physiol…