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Osanetant

National Institutes of Health

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SR 142801

Papers overview

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Highly Cited
2014
Highly Cited
2014
A Role for Tac2, NkB, and Nk3 Receptor in Normal and Dysregulated Fear Memory Consolidation
Review
2011
Review
2011
Tachykinin neurokinin 3 receptor antagonists: a patent review (2005 – 2010)
Introduction: The neurokinin 3 (NK3) receptor is a GPCR that has been shown to modulate monoaminergic systems within regions of… 
2009
2009
Augmentation of antipsychotic-induced neurochemical changes by the NK3 receptor antagonist talnetant (SB-223412)
2008
2008
The tachykinin NK3 receptor agonist senktide induces locomotor activity in male Mongolian gerbils.
Highly Cited
2006
Highly Cited
2006
Gateways to clinical trials.
Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data in the… 
Highly Cited
2006
Highly Cited
2006
Selective blockade of NK2 or NK3 receptors produces anxiolytic- and antidepressant-like effects in gerbils
Review
2006
Review
2006
Defensive and pathological functions of the gastrointestinal NK3 receptor.
2005
2005
Randomized, double-blind study of SR142801 (Osanetant). A novel neurokinin-3 (NK3) receptor antagonist in panic disorder with pre- and posttreatment cholecystokinin tetrapeptide (CCK-4) challenges.
OBJECTIVE The present study was designed to examine the efficacy and tolerability of the non-peptide neurokinin-3 (NK3) receptor… 
Review
2001
Review
2001
Osanetant Sanofi-Synthélabo.
Osanetant is a neurokinin (NK3) receptor antagonist under development by Sanofi-Synthélabo (formerly Sanofi) as a potential… 
1997
1997
A tachykinin NK3 receptor antagonist, SR 142801 (osanetant), prevents substance P-induced bronchial hyperreactivity in guinea-pigs.
Aerosolized substance P (0.1 M, for 30 min) induced airway hyperresponsiveness in guinea-pigs 24 h after they were pre-treated… 
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