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Org 6001

Known as: Org-6001 
National Institutes of Health

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amafolone

Papers overview

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1982
1982
VOLTAGE‐ AND TIME‐DEPENDENT DEPRESSION OF MAXIMUM RATE OF DEPOLARIZATION OF GUINEA‐PIG VENTRICULAR ACTION POTENTIALS BY TWO STEROIDAL ANTIARRHYTHMIC DRUGS, CCI 22277 AND ORG 6001
1 The voltage‐ and time‐dependence of the depression of the maximum rate of depolarization (V̇max) by two steroidal anti… 
1982
1982
ANTIARRHYTHMIC EFFECTS OF ORG 6001 IN RATS: CORRELATION WITH PLASMA AND TISSUE DRUG CONCENTRATIONS
1 The antiarrhythmic effects of Org 6001 following oral administration in the rat have been assessed and correlated with plasma… 
1981
1981
ANTIFIBRILLATORY EFFICACY OF ENCAINIDE, LORCAINIDE AND ORG 6001 COMPARED WITH LIGNOCAINE IN ISOLATED HEARTS OF RABBITS AND GUINEA‐PIGS
1 In Langendorff‐perfused rabbit hearts, electrical stimulation threshold and ventricular fibrillation threshold (VFT) were… 
1980
1980
The Effects of Prolonged Oral Administration of a New Antidysrhythmic Drug (Org 6001) on Coronary Artery Ligation Dysrhythmias in Conscious and Anesthetized Rats
We determined the antidysrhythmic activity of acute or prolonged administration of Org 6001 on dysrhythmias following coronary… 
1980
1980
Effect of Org 6001 on Reperfusion Dysrhythmias and Lactate Dehydrogenase Release in Isolated Rat Hearts: Comparison with Propranolol and Lignocaine
The antidysrhythmic agent Org 6001 (3.9–31.2 mg/liter) was compared with lignocaine and propranolol (3.6–14.5 and 1.3 mg/liter… 
1980
1980
COMPARATIVE ELECTROPHYSIOLOGICAL EFFECTS OF Org 6001, A NEW ORALLY ACTIVE ANTIDYSRHYTHMIC AGENT, AND LIGNOCAINE ON HUMAN VENTRICULAR MUSCLE
1 The electrophysiological effects of Org 6001, a new orally active antidysrhythmic agent, have been compared with those of… 
1979
1979
THE EFFECT OF THE AMINOSTEROID, ORG 6001, ON HYPOTHERMIA‐INDUCED VENTRICULAR FIBRILLATION IN THE CAT
1 The effect of the antidysrhythmic aminosteroid, ORG 6001, on hypothermia‐induced ventricular fibrillation was investigated in… 
1979
1979
Coronary artery ligation in anaesthetized rats as a model for the assessment of antidysrhythmic activity; the effects of lignocaine, propranolol and ORG 6001 [proceedings].
Ligation of the left coronary artery in rats provides a relatively simple model for the assessment of antidysrhythmic compounds… 
1977
1977
THE ANTIDYSRHYTHMIC AMINOSTEROID, ORG 6001, REDUCES THE ST‐SEGMENT ELEVATION PRODUCED BY CORONARY OCCLUSION IN THE DOG
ST‐segment elevation following temporary coronary artery occlusion was measured from nine epicardial leads in open‐chest… 
1976
1976
Antiarrhythmic and hemodynamic effects of an aminosteroid (Org 3001) in the digitalized dog.
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