Optic Atrophy

Known as: Optic Atrophy [Disease/Finding], atrophy nerves optic, Optic atrophy, unspecified 
Atrophy of the optic disk which may be congenital or acquired. This condition indicates a deficiency in the number of nerve fibers which arise in the… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Mitochondria play a key role in maintaining cellular metabolic homeostasis. These organelles have a high plasticity and are… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Mutations in OPA1, a dynamin-related GTPase involved in mitochondrial fusion, cristae organization and control of apoptosis, have… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2007
Highly Cited
2007
OPA1 is a ubiquitously expressed, nuclear dynamin-related GTPase, targeted to the inner mitochondrial membrane, which plays a… (More)
Is this relevant?
Review
2004
Review
2004
Mitochondria are increasingly recognized as central players in the life and death of cells and especially of neurons. The energy… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • table 2
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Autosomal dominant optic atrophy (ADOA) is the most prevalent hereditary optic neuropathy resulting in progressive loss of visual… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
Is this relevant?
Review
1999
Review
1999
Optic nerve diseases, such as the glaucomas, lead to changes in the intrapapillary and parapapillary region of the optic nerve… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Wolfram syndrome (WFS; OMIM 222300) is an autosomal recessive neurodegenerative disorder defined by young-onset non-immune… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 3
  • table 1
Is this relevant?
Review
1998
Review
1998
Inherited optic neuropathies are a significant cause of childhood and adult blindness and dominant optic atrophy (DOA) is the… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
1998
Highly Cited
1998
PURPOSE To characterize ocular abnormalities associated with iris atrophy in DBA/2J mice and to determine whether mice of this… (More)
  • table 1
  • table 2
  • figure 4
  • figure 5
  • figure 6
Is this relevant?
Highly Cited
1979
Highly Cited
1979
Of a family with 40 members, 12 had autosomal dominant optic atrophy. The affected members were aware of reduced vision from the… (More)
Is this relevant?