Oncogenicity

A measurement of the cell immortalization potential of an agent.
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
SOX9 [sex-determining region Y (SRY)-box 9 protein], a high mobility group box transcription factor, plays critical roles during… (More)
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Highly Cited
2009
Highly Cited
2009
The serine/threonine kinase Akt (cellular homolog of murine thymoma virus akt8 oncogene), also known as PKB (protein kinase B… (More)
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Highly Cited
2006
Highly Cited
2006
The PIK3CA gene, coding for the catalytic subunit p110alpha of class IA phosphatidylinositol 3-kinases (PI3Ks), is frequently… (More)
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Review
2006
Review
2006
Human papillomaviruses (HPVs) are small double-stranded DNA viruses that infect the cutaneous and mucosal epithelium. Infection… (More)
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Highly Cited
2006
Highly Cited
2006
Mouse bone marrow cells transduced with retroviral vectors encoding either of two oncogenic Bcr-Abl isoforms (p210(Bcr-Abl) and… (More)
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Highly Cited
1998
Highly Cited
1998
The serine-threonine kinase Akt is a downstream target of phosphoinositide 3-kinase (PI 3-kinase); it is activated by the… (More)
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Highly Cited
1995
Highly Cited
1995
A lifetime oncogenicity study in Fischer 344 rats was conducted to accurately characterize the carcinogenic potency of acrylamide… (More)
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Highly Cited
1989
Highly Cited
1989
Mouse 3T3 cell lines capable of constitutively synthesizing an RNA complementary to the messenger RNA encoding TIMP, tissue… (More)
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Highly Cited
1986
Highly Cited
1986
Male and female Fischer 344 rats were maintained on treated drinking water providing dosages of 0 (controls), 0.01, 0.1, 0.5, or… (More)
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Highly Cited
1983
Highly Cited
1983
The soil bacterium Agrobacterium tumefaciens is a plant pathogen that causes crown-gall tumours after infection of wounded… (More)
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