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Oncogenicity

A measurement of the cell immortalization potential of an agent.
National Institutes of Health

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Clinical Data Interchange Standards Consortium Terminology

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Highly Cited
1986
Highly Cited
1986
Activation of oncogenicity of the c-rel proto-oncogene
Reticuloendotheliosis virus strain T (Rev-T) induces a lethal lymphoma in young birds and transforms avian lymphoid cells in… 
Highly Cited
1981
Highly Cited
1981
Tissue-dependent enzyme-mediated repair or removal of O-ethyl pyrimidines and ethyl purines in carcinogen-treated rats.
Treatment of perinatal rats with N-ethyl-N-nitrosourea (EtNU) leads predominantly to brain tumors. The DNA in tissues of 10-day… 
1981
1981
Generation of highly metastatic tumors in DBA/2 mice. Oncogenicity of a strain tumor cells.
The sequential intraperitoneal injection of five different A strain tumors into DBA/2 mice resulted in the de novo generation of… 
1979
1979
Oncogenicity of simian virus 40 deletion mutants that induce altered 17-kilodalton t-proteins.
Plaque-purified viable simian virus 40 deletion mutants containing deletions between map positions 0.54 and 0.59 induced tumors… 
1976
1976
Infectivity, oncogenicity and transforming ability of BK virus and BK virus DNA.
The human papovavirus, BK, appeared weakly oncogenic in newborn hamsters and was able to induce in vitro transformation of rat… 
1974
1974
Oncogenicity of an Endogenous C-Type Virus Chemically Activated from Mouse Cells in Culture
RNA C-type viruses are known to exist in an unexpressed form in all mouse cells. These endogenous viruses can be activated from… 
Highly Cited
1973
Highly Cited
1973
Oncogenicity of non-transforming mutants of avian sarcoma viruses.
For practical purposes avian RNA tumour viruses have been divided into sarcoma and leukosis viruses. Sarcoma viruses have the… 
1972
1972
Turkey herpesvirus: lack of oncogenicity for turkeys.
SUMMARY No gross or microscopic neoplastic lesions were observed in over 300 turkeys of 3 commercial strains which were… 
Highly Cited
1971
Highly Cited
1971
Oncogenicity of herpesvirus saimiri in marmoset monkeys.
1970
1970
Studies on the oncogenicity of 3-hydroxyxanthine.
The oncogenicity of the purine N -oxide, 3-hydroxyxanthine, was tested in newborn and weanling ICR/Ha mice and in newborn…