Oncogene Protein p65(gag-jun)

Known as: jun Oncogene Protein, v-jun, Oncogene Protein, Fusion Proteins, gag-jun 
Transforming protein coded by jun oncogenes (GENES, JUN). This is a gag-onc fusion protein of about 65 kDa derived from avian sarcoma virus. v-jun… (More)
National Institutes of Health

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In BloodProcess of secretionagonistsantagonists & inhibitors
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Papers overview

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2013
2013
Loss of connective tissue growth factor as an unfavorable prognosis factor activates miR-18b by PI3K/AKT/C-Jun and C-Myc and promotes cell growth in nasopharyngeal carcinoma
Connective tissue growth factor (CTGF) has different roles in different types of cancer. However, the involvement and molecular… (More)
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2012
2012
Perifosine sensitizes UVB-induced apoptosis in skin cells: new implication of skin cancer prevention?
We demonstrate here that a relative low dose of perifosine significantly enhanced UVB-induced apoptosis in skin cells… (More)
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2011
2011
CYLD inhibits tumorigenesis and metastasis by blocking JNK/AP1 signaling at multiple levels.
CYLD has been recognized as a tumor suppressor due to its dominant genetic linkage to multiple types of epidermal tumors and a… (More)
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Highly Cited
2008
Highly Cited
2008
Increased c-Jun-NH2-kinase signaling in neurofibromatosis-1 heterozygous microglia drives microglia activation and promotes optic glioma proliferation.
Neurofibromatosis-1 (NF1) is a common tumor predisposition syndrome in which affected individuals develop benign and malignant… (More)
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2007
2007
Breast cancer expressing the activated HER2/neu is sensitive to gefitinib in vitro and in vivo and acquires resistance through a novel point mutation in the HER2/neu.
The HER2/neu oncogene is an important diagnostic and prognostic factor and therapeutic target in breast and other cancers. We… (More)
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2005
2005
Detailed mapping of the nuclear export signal in the Rous sarcoma virus Gag protein.
The Rous sarcoma virus (RSV) Gag polyprotein undergoes transient nuclear trafficking as an intrinsic part of the virus assembly… (More)
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2001
2001
The c-Jun NH2-terminal kinase3 (JNK3) gene: genomic structure, chromosomal assignment, and loss of expression in brain tumors
AbstractBy examining 19 human cell lines derived from brain tumors for altered expression of expressed sequence tags (ESTs) in… (More)
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1997
1997
Effects of the inhibition of p38/RK MAP kinase on induction of five fos and jun genes by diverse stimuli
The ERK, JNK/SAPK and p38/RK MAP kinase subtypes are differentially activated by physiological, pharmacological and stress… (More)
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Highly Cited
1995
Highly Cited
1995
Stimulation of ionotropic glutamate receptors activates transcription factor NF-kappa B in primary neurons.
L-Glutamate is the most common excitatory neurotransmitter in the brain and plays a crucial role in neuronal plasticity as well… (More)
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1988
1988
v-jun encodes a nuclear protein with enhancer binding properties of AP-1.
The jun oncogene of ASV17 is expressed as a 65 kd protein (p65gag-jun) that contains partial gag sequences at its amino terminus… (More)
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